Recombinant multi-species RHOC/RhoC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RHOC/RhoC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ARH9,ARHC,Arh9,Arhc,H9,RHOC,RHOH9,Rho cDNA clone 9 (h9),Rho-related GTP-binding protein RhoC,RhoC,Rhoc

Target products collectionGo to RHOC/RhoC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IO127-Ag-1/ GM-Tg-hg-IO127-Ag-2 Human RHOC/RhoC protein Human
GM-Tg-rg-IO127-Ag-1/ GM-Tg-rg-IO127-Ag-2 Rat RHOC/RhoC protein Rat
GM-Tg-mg-IO127-Ag-1/ GM-Tg-mg-IO127-Ag-2 Mouse RHOC/RhoC protein Mouse
GM-Tg-cynog-IO127-Ag-1/ GM-Tg-cynog-IO127-Ag-2 Cynomolgus/Rhesus macaque RHOC/RhoC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IO127-Ag-1/ GM-Tg-felg-IO127-Ag-2 Feline RHOC/RhoC protein Feline
GM-Tg-cang-IO127-Ag-1/ GM-Tg-cang-IO127-Ag-2 Canine RHOC/RhoC protein Canine
GM-Tg-bovg-IO127-Ag-1/ GM-Tg-bovg-IO127-Ag-2 Bovine RHOC/RhoC protein Bovine
GM-Tg-equg-IO127-Ag-1/ GM-Tg-equg-IO127-Ag-2 Equine RHOC/RhoC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IO127-Ag-1/ GM-Tg-hg-IO127-Ag-2; GM-Tg-rg-IO127-Ag-1/ GM-Tg-rg-IO127-Ag-2;
GM-Tg-mg-IO127-Ag-1/ GM-Tg-mg-IO127-Ag-2; GM-Tg-cynog-IO127-Ag-1/ GM-Tg-cynog-IO127-Ag-2;
GM-Tg-felg-IO127-Ag-1/ GM-Tg-felg-IO127-Ag-2; GM-Tg-cang-IO127-Ag-1/ GM-Tg-cang-IO127-Ag-2;
GM-Tg-bovg-IO127-Ag-1/ GM-Tg-bovg-IO127-Ag-2; GM-Tg-equg-IO127-Ag-1/ GM-Tg-equg-IO127-Ag-2
Products Name RHOC/RhoC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RHOC/RhoC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RHOC/RhoC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.