Explore IL-17RC/IL17RC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
| Target ID |
GM-TA144
|
| Target Name |
IL-17RC/IL17RC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
84818
|
| Gene ID |
100058271 (Equus caballus), 101092091 (Felis catus), 171095 (Mus musculus), 297520 (Rattus norvegicus)
504855 (Bos taurus), 610118 (Canis lupus familiaris), 699223 (Macaca mulatta), 84818 (Homo sapiens)
|
| Target Alternative Names |
1110025H02Rik,CANDF9,Gm19850,IL-17 receptor C,IL-17RC,IL17-RC,IL17-RL,IL17RC,IL17RL,Il17rc,Il17rl,Interleukin-17 receptor C,Interleukin-17 receptor homolog (IL17Rhom),Interleukin-17 receptor-like protein (IL-17RL),ZcytoR14
|
| Uniprot Accession |
Q8K4C2,Q8NAC3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000009634, ENSMUSG00000030281, ENSBTAG00000033669, ENSCAFG00845008567, ENSMMUG00000018282, ENSG00000163702
|
| Target Classification |
Cytokine Receptor
|
IL-17RC/IL17RC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84818 | Pre-made Human IL17RC/CANDF9/IL17RL siRNA oligo Duplex | 84818 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo297520 | Pre-made Rat Il17rc siRNA oligo Duplex | 297520 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171095 | Pre-made Mouse Il17rc/Il17rl/Gm19850 siRNA oligo Duplex | 171095 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699223 | Pre-made Cynomolgus/Rhesus macaque IL17RC siRNA oligo Duplex | 699223 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092091 | Pre-made Cat/Feline IL17RC siRNA oligo Duplex | 101092091 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610118 | Pre-made Dog/Canine IL17RC siRNA oligo Duplex | 610118 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504855 | Pre-made Bovines/Cattle IL17RC siRNA oligo Duplex | 504855 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058271 | Pre-made Equine/Horse IL17RC siRNA oligo Duplex | 100058271 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-17RC/IL17RC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA144-Ab | Human | Anti-Human IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-TA144-Ab | Rat | Anti-Rat IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-TA144-Ab | Mouse | Anti-Mouse IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-TA144-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-TA144-Ab | Cat/Feline | Anti-Cat/Feline IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-TA144-Ab | Dog/Canine | Anti-Dog/Canine IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-TA144-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-TA144-Ab | Equine/Horse | Anti-Equine/Horse IL-17RC/IL17RC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-17RC/IL17RC VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA144-Ag | Human | Human IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA144-Ag | Rat | Rat IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA144-Ag | Mouse | Mouse IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA144-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA144-Ag | Cat/Feline | Cat/Feline IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA144-Ag | Dog/Canine | Dog/Canine IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA144-Ag | Bovines/Cattle | Bovines/Cattle IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA144-Ag | Equine/Horse | Equine/Horse IL-17RC/IL17RC VLP (virus-like particle) | HEK293 | Products Developing |
