Explore IDH3A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA143
|
| Target Name |
IDH3A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3419
|
| Gene ID |
100060114 (Equus caballus), 101085721 (Felis catus), 114096 (Rattus norvegicus), 282446 (Bos taurus) 3419 (Homo sapiens), 479066 (Canis lupus familiaris), 677715 (Macaca mulatta), 67834 (Mus musculus)
|
| Target Alternative Names |
1110003P10Rik,1500012E04Rik,BG1,IDH3A,Idh3a,Isocitrate dehydrogenase [NAD] subunit alpha,Isocitric dehydrogenase subunit alpha,NAD(+)-specific ICDH subunit alpha,RP90,mitochondrial
|
| Uniprot Accession |
Q99NA5,P41563,P50213,P54836,Q9D6R2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000015278, ENSBTAG00000006227, ENSG00000166411, ENSCAFG00845006975, ENSMMUG00000011838, ENSMUSG00000032279
|
Pre-made viral vector of IDH3A cDNA Clones/ORF Plasmid
IDH3A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3419 | Pre-made Human IDH3A/RP90 siRNA oligo Duplex | 3419 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114096 | Pre-made Rat Idh3a siRNA oligo Duplex | 114096 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67834 | Pre-made Mouse Idh3a/1110003P10Rik/1500012E04Rik siRNA oligo Duplex | 67834 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo677715 | Pre-made Cynomolgus/Rhesus macaque IDH3A siRNA oligo Duplex | 677715 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085721 | Pre-made Cat/Feline IDH3A siRNA oligo Duplex | 101085721 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479066 | Pre-made Dog/Canine IDH3A siRNA oligo Duplex | 479066 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282446 | Pre-made Bovines/Cattle IDH3A/BG1 siRNA oligo Duplex | 282446 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060114 | Pre-made Equine/Horse IDH3A siRNA oligo Duplex | 100060114 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IDH3A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA143-Ab | Human | Anti-Human IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA143-Ab | Rat | Anti-Rat IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA143-Ab | Mouse | Anti-Mouse IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA143-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA143-Ab | Cat/Feline | Anti-Cat/Feline IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA143-Ab | Dog/Canine | Anti-Dog/Canine IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA143-Ab | Bovines/Cattle | Anti-Bovines/Cattle IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA143-Ab | Equine/Horse | Anti-Equine/Horse IDH3A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
IDH3A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA143-Ag | Human | Human IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA143-Ag | Rat | Rat IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA143-Ag | Mouse | Mouse IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA143-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA143-Ag | Cat/Feline | Cat/Feline IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA143-Ag | Dog/Canine | Dog/Canine IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA143-Ag | Bovines/Cattle | Bovines/Cattle IDH3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA143-Ag | Equine/Horse | Equine/Horse IDH3A recombinant protein | Mammalian cell | Detail |