Explore ATP1A3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
| Target ID |
GM-TA133
|
| Target Name |
ATP1A3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
478
|
| Gene ID |
100069796 (Equus caballus), 232975 (Mus musculus), 24213 (Rattus norvegicus), 282598 (Bos taurus)
478 (Homo sapiens), 612463 (Canis lupus familiaris), 706513 (Macaca mulatta)
|
| Target Alternative Names |
AHC2,ATP1A1,ATP1A3,Atp1a3,Atpa-2,Atpa1a3,CAPOS,DEE99,DYT12,Na(+)/K(+) ATPase alpha(III) subunit,Na(+)/K(+) ATPase alpha-3 subunit,RDP,Sodium pump subunit alpha-3,Sodium/potassium-transporting ATPase subunit alpha-3
|
| Uniprot Accession |
Q6PIC6,P06687,P13637
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cGMP-PKG signaling pathway, cAMP signaling pathway, Adrenergic signaling in cardiomyocytes, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption
|
| Gene Ensembl |
ENSECAG00000024155, ENSMUSG00000040907, ENSBTAG00000018635, ENSG00000105409, ENSCAFG00845001235, ENSMMUG00000017427
|
ATP1A3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo478 | Pre-made Human ATP1A3/RDP/AHC2 siRNA oligo Duplex | 478 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24213 | Pre-made Rat Atp1a3/Atpa1a3 siRNA oligo Duplex | 24213 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo232975 | Pre-made Mouse Atp1a3/Atpa-2 siRNA oligo Duplex | 232975 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706513 | Pre-made Cynomolgus/Rhesus macaque ATP1A3 siRNA oligo Duplex | 706513 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612463 | Pre-made Dog/Canine ATP1A3 siRNA oligo Duplex | 612463 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282598 | Pre-made Bovines/Cattle ATP1A3 siRNA oligo Duplex | 282598 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069796 | Pre-made Equine/Horse ATP1A3 siRNA oligo Duplex | 100069796 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ATP1A3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA133-Ab | Human | Anti-Human ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA133-Ab | Rat | Anti-Rat ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA133-Ab | Mouse | Anti-Mouse ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA133-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA133-Ab | Dog/Canine | Anti-Dog/Canine ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA133-Ab | Bovines/Cattle | Anti-Bovines/Cattle ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA133-Ab | Equine/Horse | Anti-Equine/Horse ATP1A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ATP1A3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA133-Ag | Human | Human ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA133-Ag | Rat | Rat ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA133-Ag | Mouse | Mouse ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA133-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA133-Ag | Dog/Canine | Dog/Canine ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA133-Ag | Bovines/Cattle | Bovines/Cattle ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA133-Ag | Equine/Horse | Equine/Horse ATP1A3 VLP (virus-like particle) | HEK293 | Products Developing |
