STAT5B Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore STAT5B gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]

STAT5B siRNA/miRNA/oligo for RNA interfence (RNAi)

STAT5B antibody/GMab

STAT5B recombinant protein