Explore SGMS2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.[provided by RefSeq, Oct 2008]
| Target ID |
GM-TA108
|
| Target Name |
SGMS2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
166929
|
| Gene ID |
100072971 (Equus caballus), 101088574 (Felis catus), 166929 (Homo sapiens), 310849 (Rattus norvegicus)
478505 (Canis lupus familiaris), 520954 (Bos taurus), 695947 (Macaca mulatta), 74442 (Mus musculus)
|
| Target Alternative Names |
4933405A16Rik,5133401H06Rik,CDL,Phosphatidylcholine:ceramide cholinephosphotransferase 2,RGD1305778,SGMS2,SMS2,Sgms2,Sphingomyelin synthase 2 (SMS2),spermatin
|
| Uniprot Accession |
Q8NHU3,Q4JM44,Q9D4B1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Sphingolipid signaling pathway, Sphingolipid metabolism
|
| Gene Ensembl |
ENSECAG00000021665, ENSG00000164023, ENSCAFG00845028905, ENSBTAG00000016805, ENSMMUG00000017834, ENSMUSG00000050931
|
Pre-made viral vector of SGMS2 cDNA Clones/ORF Plasmid
SGMS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo166929 | Pre-made Human SGMS2/CDL/SMS2 siRNA oligo Duplex | 166929 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310849 | Pre-made Rat Sgms2/spermatin/RGD1305778 siRNA oligo Duplex | 310849 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74442 | Pre-made Mouse Sgms2/4933405A16Rik/5133401H06Rik siRNA oligo Duplex | 74442 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695947 | Pre-made Cynomolgus/Rhesus macaque SGMS2 siRNA oligo Duplex | 695947 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088574 | Pre-made Cat/Feline SGMS2 siRNA oligo Duplex | 101088574 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478505 | Pre-made Dog/Canine SGMS2 siRNA oligo Duplex | 478505 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520954 | Pre-made Bovines/Cattle SGMS2 siRNA oligo Duplex | 520954 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072971 | Pre-made Equine/Horse SGMS2 siRNA oligo Duplex | 100072971 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SGMS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA108-Ab | Human | Anti-Human SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA108-Ab | Rat | Anti-Rat SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA108-Ab | Mouse | Anti-Mouse SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA108-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA108-Ab | Cat/Feline | Anti-Cat/Feline SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA108-Ab | Dog/Canine | Anti-Dog/Canine SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA108-Ab | Bovines/Cattle | Anti-Bovines/Cattle SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA108-Ab | Equine/Horse | Anti-Equine/Horse SGMS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SGMS2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA108-Ag | Human | Human SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA108-Ag | Rat | Rat SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA108-Ag | Mouse | Mouse SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA108-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA108-Ag | Cat/Feline | Cat/Feline SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA108-Ag | Dog/Canine | Dog/Canine SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA108-Ag | Bovines/Cattle | Bovines/Cattle SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA108-Ag | Equine/Horse | Equine/Horse SGMS2 VLP (virus-like particle) | HEK293 | Products Developing |
