Explore Fibrinogen Beta Chain/FGB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Aug 2020]
| Target ID |
GM-TA100
|
| Target Name |
Fibrinogen Beta Chain/FGB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2244
|
| Gene ID |
100069774 (Equus caballus), 101099632 (Felis catus), 110135 (Mus musculus), 2244 (Homo sapiens)
24366 (Rattus norvegicus), 475472 (Canis lupus familiaris), 510522 (Bos taurus), 698487 (Macaca mulatta)
|
| Target Alternative Names |
FGB,Fgb,2510049G14Rik,HEL-S-78p,Ab1-181,Ab1-216,Ac1-581
|
| Uniprot Accession |
P68121,P14469,Q8K0E8,P02675,P14480,P02677,P02676
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Malignant neoplasm of bladder, Ovarian cancer, Juvenile arthritis, Pulmonary embolism
|
| Disease from KEGG |
Complement and coagulation cascades, Platelet activation
|
| Gene Ensembl |
ENSECAG00000010239, ENSMUSG00000033831, ENSG00000171564, ENSCAFG00845009700, ENSBTAG00000022120, ENSMMUG00000021302
|
| Target Classification |
|
Pre-made viral vector of Fibrinogen Beta Chain/FGB cDNA Clones/ORF Plasmid
Fibrinogen Beta Chain/FGB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2244 | Pre-made Human FGB/HEL-S-78p siRNA oligo Duplex | 2244 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24366 | Pre-made Rat Fgb/Ab1-181/Ab1-216 siRNA oligo Duplex | 24366 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110135 | Pre-made Mouse Fgb/2510049G14Rik siRNA oligo Duplex | 110135 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698487 | Pre-made Cynomolgus/Rhesus macaque FGB siRNA oligo Duplex | 698487 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099632 | Pre-made Cat/Feline FGB siRNA oligo Duplex | 101099632 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475472 | Pre-made Dog/Canine FGB siRNA oligo Duplex | 475472 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510522 | Pre-made Bovines/Cattle FGB siRNA oligo Duplex | 510522 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069774 | Pre-made Equine/Horse FGB siRNA oligo Duplex | 100069774 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Fibrinogen Beta Chain/FGB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA100-Ab | Human | Anti-Human Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA100-Ab | Rat | Anti-Rat Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA100-Ab | Mouse | Anti-Mouse Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA100-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA100-Ab | Cat/Feline | Anti-Cat/Feline Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA100-Ab | Dog/Canine | Anti-Dog/Canine Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA100-Ab | Bovines/Cattle | Anti-Bovines/Cattle Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA100-Ab | Equine/Horse | Anti-Equine/Horse Fibrinogen Beta Chain/FGB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Fibrinogen Beta Chain/FGB VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA100-Ag | Human | Human Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA100-Ag | Rat | Rat Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA100-Ag | Mouse | Mouse Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA100-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA100-Ag | Cat/Feline | Cat/Feline Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA100-Ag | Dog/Canine | Dog/Canine Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA100-Ag | Bovines/Cattle | Bovines/Cattle Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA100-Ag | Equine/Horse | Equine/Horse Fibrinogen Beta Chain/FGB VLP (virus-like particle) | HEK293 | Products Developing |
