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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
| Target ID |
GM-TA095
|
| Target Name |
FCGR3B/CD16b
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2215
|
| Gene ID |
2215 (Homo sapiens)
|
| Target Alternative Names |
CD16,CD16-I,CD16A,CD16b,FCG3,FCGR3,FCGR3A,FCGR3B,FCR-10,FCRIII,FCRIIIb,Fc-gamma RIII,Fc-gamma RIII-beta (CD16-I,Fc-gamma RIIIb,FcR-10,FcRIII,FcRIIIb),IgG Fc receptor III-1,Low affinity immunoglobulin gamma Fc region receptor III-B
|
| Uniprot Accession |
O75015
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Phagosome, Osteoclast differentiation, Natural killer cell mediated cytotoxicity, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis
|
| Gene Ensembl |
ENSG00000162747
|
Pre-made viral vector of FCGR3B/CD16b cDNA Clones/ORF Plasmid
FCGR3B/CD16b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2215 | Pre-made Human FCGR3B/CD16/FCG3 siRNA oligo Duplex | 2215 | Human | In-vitro grade; in-vivo grade | Detail |
FCGR3B/CD16b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA095-Ab | Human | Anti-Human FCGR3B/CD16b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FCGR3B/CD16b VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA095-Ag | Human | Human FCGR3B/CD16b VLP (virus-like particle) | HEK293 | Products Developing |