Explore GABBR2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
| Target ID |
GM-TA094
|
| Target Name |
GABBR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9568
|
| Gene ID |
100063963 (Equus caballus), 101093058 (Felis catus), 242425 (Mus musculus), 481627 (Canis lupus familiaris)
517040 (Bos taurus), 718019 (Macaca mulatta), 83633 (Rattus norvegicus), 9568 (Homo sapiens)
|
| Target Alternative Names |
DEE59,EIEE59,G-protein coupled receptor 51,GABA-B receptor 2,GABA-B-R2,GABA-BR2,GABABR2,GABBR2,GPR51,GPRC3B,Gabbr2,Gamma-aminobutyric acid type B receptor subunit 2,Gb2,Gm425,Gpr51,HG20,HRIHFB2099,NDPLHS
|
| Uniprot Accession |
Q80T41,O88871,O75899
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000009066, ENSMUSG00000039809, ENSCAFG00845006883, ENSBTAG00000013810, ENSMMUG00000009832, ENSG00000136928
|
| Target Classification |
GPCR
|
Pre-made viral vector of GABBR2 cDNA Clones/ORF Plasmid
GABBR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9568 | Pre-made Human GABBR2/HG20/DEE59 siRNA oligo Duplex | 9568 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83633 | Pre-made Rat Gabbr2/Gpr51 siRNA oligo Duplex | 83633 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo242425 | Pre-made Mouse Gabbr2/Gb2/Gm425 siRNA oligo Duplex | 242425 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718019 | Pre-made Cynomolgus/Rhesus macaque GABBR2 siRNA oligo Duplex | 718019 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093058 | Pre-made Cat/Feline GABBR2 siRNA oligo Duplex | 101093058 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481627 | Pre-made Dog/Canine GABBR2 siRNA oligo Duplex | 481627 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517040 | Pre-made Bovines/Cattle GABBR2 siRNA oligo Duplex | 517040 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063963 | Pre-made Equine/Horse GABBR2 siRNA oligo Duplex | 100063963 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABBR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA094-Ab | Human | Anti-Human GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA094-Ab | Rat | Anti-Rat GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA094-Ab | Mouse | Anti-Mouse GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA094-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA094-Ab | Cat/Feline | Anti-Cat/Feline GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA094-Ab | Dog/Canine | Anti-Dog/Canine GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA094-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA094-Ab | Equine/Horse | Anti-Equine/Horse GABBR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABBR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA094-Ag | Human | Human GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA094-Ag | Rat | Rat GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA094-Ag | Mouse | Mouse GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA094-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA094-Ag | Cat/Feline | Cat/Feline GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA094-Ag | Dog/Canine | Dog/Canine GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA094-Ag | Bovines/Cattle | Bovines/Cattle GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA094-Ag | Equine/Horse | Equine/Horse GABBR2 VLP (virus-like particle) | HEK293 | Products Developing |
