gp130/IL6ST/CD130 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore gp130/IL6ST/CD130 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]

Pre-made viral vector of gp130/IL6ST/CD130 cDNA Clones/ORF Plasmid

gp130/IL6ST/CD130 siRNA/miRNA/oligo for RNA interfence (RNAi)

gp130/IL6ST/CD130 antibody/GMab

gp130/IL6ST/CD130 VLP (virus-like particle)/protein