Explore IL-17RB/IL17RB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA074
|
| Target Name |
IL-17RB/IL17RB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
55540
|
| Gene ID |
100059421 (Equus caballus), 101080437 (Felis catus), 306247 (Rattus norvegicus), 476587 (Canis lupus familiaris)
50905 (Mus musculus), 533605 (Bos taurus), 55540 (Homo sapiens), 693671 (Macaca mulatta)
|
| Target Alternative Names |
CRL4,Cytokine receptor-like 4,EVI27,Evi27,IL-17 receptor B,IL-17 receptor homolog 1 (IL-17Rh1,IL-17ER,IL-17RB,IL-17Rh1,IL17BR,IL17RB,IL17RH1,IL17Rh1),Il17br,Il17rb,Interleukin-17 receptor B,Interleukin-17B receptor (IL-17B receptor)
|
| Uniprot Accession |
Q9JIP3,Q9NRM6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, IL-17 signaling pathway
|
| Gene Ensembl |
ENSECAG00000004258, ENSCAFG00845027332, ENSMUSG00000015966, ENSG00000056736, ENSMMUG00000019267
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL-17RB/IL17RB cDNA Clones/ORF Plasmid
IL-17RB/IL17RB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55540 | Pre-made Human IL17RB/CRL4/EVI27 siRNA oligo Duplex | 55540 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306247 | Pre-made Rat Il17rb siRNA oligo Duplex | 306247 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50905 | Pre-made Mouse Il17rb/Evi27/Il17br siRNA oligo Duplex | 50905 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693671 | Pre-made Cynomolgus/Rhesus macaque IL17RB siRNA oligo Duplex | 693671 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080437 | Pre-made Cat/Feline IL17RB siRNA oligo Duplex | 101080437 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476587 | Pre-made Dog/Canine IL17RB siRNA oligo Duplex | 476587 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533605 | Pre-made Bovines/Cattle IL17RB siRNA oligo Duplex | 533605 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059421 | Pre-made Equine/Horse IL17RB siRNA oligo Duplex | 100059421 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-17RB/IL17RB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA074-Ab | Human | Anti-Human IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-TA074-Ab | Rat | Anti-Rat IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-TA074-Ab | Mouse | Anti-Mouse IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-TA074-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-TA074-Ab | Cat/Feline | Anti-Cat/Feline IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-TA074-Ab | Dog/Canine | Anti-Dog/Canine IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-TA074-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-TA074-Ab | Equine/Horse | Anti-Equine/Horse IL-17RB/IL17RB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-17RB/IL17RB VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA074-Ag | Human | Human IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA074-Ag | Rat | Rat IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA074-Ag | Mouse | Mouse IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA074-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA074-Ag | Cat/Feline | Cat/Feline IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA074-Ag | Dog/Canine | Dog/Canine IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA074-Ag | Bovines/Cattle | Bovines/Cattle IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA074-Ag | Equine/Horse | Equine/Horse IL-17RB/IL17RB VLP (virus-like particle) | HEK293 | Products Developing |
