Explore GGT1/CD224 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]
| Target ID |
GM-TA059
|
| Target Name |
GGT1/CD224
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2678
|
| Gene ID |
100050188 (Equus caballus), 101081761 (Felis catus), 116568 (Rattus norvegicus), 14598 (Mus musculus)
2678 (Homo sapiens), 486400 (Canis lupus familiaris), 615582 (Bos taurus), 707545 (Macaca mulatta)
|
| Target Alternative Names |
GGT1,Ggt1,Ggt,Ggtp,GGLUT,GGT,dwg,CD224,GGT 1,GGT-1,GTG,GGTD,D22S672,D22S732
|
| Uniprot Accession |
P07314,Q60928,P19440
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Metabolic pathways, Arachidonic acid metabolism
|
| Gene Ensembl |
ENSECAG00000000097, ENSMUSG00000006345, ENSG00000100031, ENSCAFG00845022970, ENSBTAG00000046900, ENSMMUG00000020999
|
| Target Classification |
|
GGT1/CD224 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2678 | Pre-made Human GGT1/GGT/GTG siRNA oligo Duplex | 2678 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116568 | Pre-made Rat Ggt1/Ggt/Ggtp siRNA oligo Duplex | 116568 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14598 | Pre-made Mouse Ggt1/GGT/dwg siRNA oligo Duplex | 14598 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707545 | Pre-made Cynomolgus/Rhesus macaque GGT1 siRNA oligo Duplex | 707545 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081761 | Pre-made Cat/Feline GGT1 siRNA oligo Duplex | 101081761 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486400 | Pre-made Dog/Canine GGT1 siRNA oligo Duplex | 486400 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615582 | Pre-made Bovines/Cattle GGT1 siRNA oligo Duplex | 615582 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050188 | Pre-made Equine/Horse GGT1 siRNA oligo Duplex | 100050188 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GGT1/CD224 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA059-Ab | Human | Anti-Human GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA059-Ab | Rat | Anti-Rat GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA059-Ab | Mouse | Anti-Mouse GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA059-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA059-Ab | Cat/Feline | Anti-Cat/Feline GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA059-Ab | Dog/Canine | Anti-Dog/Canine GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA059-Ab | Bovines/Cattle | Anti-Bovines/Cattle GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA059-Ab | Equine/Horse | Anti-Equine/Horse GGT1/CD224 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GGT1/CD224 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA059-Ag | Human | Human GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA059-Ag | Rat | Rat GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA059-Ag | Mouse | Mouse GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA059-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA059-Ag | Cat/Feline | Cat/Feline GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA059-Ag | Dog/Canine | Dog/Canine GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA059-Ag | Bovines/Cattle | Bovines/Cattle GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA059-Ag | Equine/Horse | Equine/Horse GGT1/CD224 VLP (virus-like particle) | HEK293 | Products Developing |
