Explore MTHFD2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
| Target ID |
GM-TA058
|
| Target Name |
MTHFD2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10797
|
| Gene ID |
100053990 (Equus caballus), 101083836 (Felis catus), 10797 (Homo sapiens), 17768 (Mus musculus)
483107 (Canis lupus familiaris), 517539 (Bos taurus), 680308 (Rattus norvegicus), 714974 (Macaca mulatta)
|
| Target Alternative Names |
MTHFD2,Mthfd2,NMDMC
|
| Uniprot Accession |
P13995,P18155,Q0P5C2
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000017419, ENSG00000065911, ENSMUSG00000005667, ENSBTAG00000004881, ENSMMUG00000009739
|
| Target Classification |
|
Pre-made viral vector of MTHFD2 cDNA Clones/ORF Plasmid
MTHFD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10797 | Pre-made Human MTHFD2/NMDMC siRNA oligo Duplex | 10797 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680308 | Pre-made Rat Mthfd2 siRNA oligo Duplex | 680308 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17768 | Pre-made Mouse Mthfd2/NMDMC siRNA oligo Duplex | 17768 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714974 | Pre-made Cynomolgus/Rhesus macaque MTHFD2 siRNA oligo Duplex | 714974 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083836 | Pre-made Cat/Feline MTHFD2 siRNA oligo Duplex | 101083836 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483107 | Pre-made Dog/Canine MTHFD2 siRNA oligo Duplex | 483107 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517539 | Pre-made Bovines/Cattle MTHFD2 siRNA oligo Duplex | 517539 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053990 | Pre-made Equine/Horse MTHFD2 siRNA oligo Duplex | 100053990 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MTHFD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA058-Ab | Human | Anti-Human MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA058-Ab | Rat | Anti-Rat MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA058-Ab | Mouse | Anti-Mouse MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA058-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA058-Ab | Cat/Feline | Anti-Cat/Feline MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA058-Ab | Dog/Canine | Anti-Dog/Canine MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA058-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA058-Ab | Equine/Horse | Anti-Equine/Horse MTHFD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MTHFD2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA058-Ag | Human | Human MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA058-Ag | Rat | Rat MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA058-Ag | Mouse | Mouse MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA058-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA058-Ag | Cat/Feline | Cat/Feline MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA058-Ag | Dog/Canine | Dog/Canine MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA058-Ag | Bovines/Cattle | Bovines/Cattle MTHFD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA058-Ag | Equine/Horse | Equine/Horse MTHFD2 recombinant protein | Mammalian cell | Detail |
