Explore POLR1A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]
| Target ID |
GM-TA057
|
| Target Name |
POLR1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
25885
|
| Gene ID |
101087313 (Felis catus), 20019 (Mus musculus), 25885 (Homo sapiens), 475766 (Canis lupus familiaris) 536316 (Bos taurus), 696963 (Macaca mulatta), 83581 (Rattus norvegicus)
|
| Target Alternative Names |
194kDa,2900087K15Rik,3010014K16Rik,A190,AFDCIN,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,HLD27,POLR1A,Polr1a,RNA polymerase I 194 kDa subunit (RPA194),RNA polymerase I subunit A1,RPA1,RPA190,RPA194,RPO1-4,RPO14,Rpa1,Rpo1-4,mRPA1
|
| Uniprot Accession |
O35134,O95602,O54889
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSMUSG00000049553, ENSG00000068654, ENSCAFG00845013628, ENSBTAG00000006481, ENSMMUG00000015815
|
POLR1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo25885 | Pre-made Human POLR1A/A190/RPA1 siRNA oligo Duplex | 25885 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83581 | Pre-made Rat Polr1a/Rpa1/Rpo1-4 siRNA oligo Duplex | 83581 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20019 | Pre-made Mouse Polr1a/mRPA1/194kDa siRNA oligo Duplex | 20019 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696963 | Pre-made Cynomolgus/Rhesus macaque POLR1A siRNA oligo Duplex | 696963 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087313 | Pre-made Cat/Feline POLR1A siRNA oligo Duplex | 101087313 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475766 | Pre-made Dog/Canine POLR1A siRNA oligo Duplex | 475766 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536316 | Pre-made Bovines/Cattle POLR1A siRNA oligo Duplex | 536316 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
POLR1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA057-Ab | Human | Anti-Human POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA057-Ab | Rat | Anti-Rat POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA057-Ab | Mouse | Anti-Mouse POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA057-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA057-Ab | Cat/Feline | Anti-Cat/Feline POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA057-Ab | Dog/Canine | Anti-Dog/Canine POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA057-Ab | Bovines/Cattle | Anti-Bovines/Cattle POLR1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
POLR1A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA057-Ag | Human | Human POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA057-Ag | Rat | Rat POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA057-Ag | Mouse | Mouse POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA057-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA057-Ag | Cat/Feline | Cat/Feline POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA057-Ag | Dog/Canine | Dog/Canine POLR1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA057-Ag | Bovines/Cattle | Bovines/Cattle POLR1A recombinant protein | Mammalian cell | Detail |