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Target
sublocation: Introcelluar Protein.
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
| Target ID |
GM-TA048
|
| Target Name |
NAT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9
|
| Gene ID |
17960 (Mus musculus), 704019 (Macaca mulatta), 9 (Homo sapiens)
|
| Target Alternative Names |
AAC1,Arylamide acetylase 1,Arylamine N-acetyltransferase 1,MNAT,Monomorphic arylamine N-acetyltransferase (MNAT),N-acetyltransferase type 1 (NAT-1),NAT-1,NAT1,NATI,Nat-1,Nat1
|
| Uniprot Accession |
P50294,P18440
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Metabolic pathways, Chemical carcinogenesis - DNA adducts
|
| Gene Ensembl |
ENSMUSG00000025588, ENSG00000171428
|
Pre-made viral vector of NAT1 cDNA Clones/ORF Plasmid
NAT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9 | Pre-made Human NAT1/AAC1/MNAT siRNA oligo Duplex | 9 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17960 | Pre-made Mouse Nat1/Nat-1 siRNA oligo Duplex | 17960 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704019 | Pre-made Cynomolgus/Rhesus macaque NAT1 siRNA oligo Duplex | 704019 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
NAT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA048-Ab | Human | Anti-Human NAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA048-Ab | Mouse | Anti-Mouse NAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA048-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
NAT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA048-Ag | Human | Human NAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA048-Ag | Mouse | Mouse NAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA048-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NAT1 recombinant protein | Mammalian cell | Detail |
