APPBP1/NAE1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore APPBP1/NAE1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Target ID GM-TA044
Target Name APPBP1/NAE1
Gene Group ldentifer
（Target Gene ID in Homo species) 		8883
Gene ID 100065540 (Equus caballus), 101086523 (Felis catus), 234664 (Mus musculus), 610026 (Canis lupus familiaris)
614491 (Bos taurus), 696429 (Macaca mulatta), 84019 (Rattus norvegicus), 8883 (Homo sapiens)
Target Alternative Names 59 kDa (APP-BP1),59kDa,A-116A10.1,APPBP1,Amyloid beta precursor protein-binding protein 1,Amyloid protein-binding protein 1,Appbp1,HPP1,NAE1,NEDD8-activating enzyme E1 regulatory subunit,NEDFIH,Nae1,Proto-oncogene protein 1,RGD1563180,ula-1
Uniprot Accession Q8VBW6,Q9Z1A5,Q13564
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG Alzheimer disease
Gene Ensembl ENSECAG00000021954, ENSMUSG00000031878, ENSCAFG00845011147, ENSBTAG00000010132, ENSMMUG00000006752, ENSG00000159593


Pre-made viral vector of APPBP1/NAE1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001402Human NAE1/A-116A10.1/APPBP1 Lentivirus plasmidNM_0010181598883HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001402Human NAE1/A-116A10.1/APPBP1 Lentivirus particleNM_0010181598883HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000934Rat Nae1/Appbp1/RGD1563180 Adenovirus plasmidNM_032072.484019RatAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMAD000934Rat Nae1/Appbp1/RGD1563180 Adenovirus particleNM_032072.484019RatAdenovirus particleNull3xflag (C-Terminal)CMVDetail
pGMAD000697Mouse Nae1/59kDa/Ap Adenovirus plasmidNM_144931234664MouseAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLPm002995Mouse Nae1/59kDa/Appbp1 Lentivirus plasmidNM_144931234664MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000339Mouse Nae1/59kDa/Ap Mammalian (Non-Viral Vector) plasmidNM_144931234664MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD000697Mouse Nae1/59kDa/Ap Adenovirus particleNM_144931234664MouseAdenovirus particleNull3xflag (C-Terminal)CMVDetail
vGMLPm002995Mouse Nae1/59kDa/Appbp1 Lentivirus particleNM_144931234664MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


APPBP1/NAE1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo8883Pre-made Human NAE1/HPP1/ula-1 siRNA oligo Duplex8883HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo84019Pre-made Rat Nae1/Appbp1/RGD1563180 siRNA oligo Duplex84019RatIn-vitro grade; in-vivo gradeDetail
pGMoligo234664Pre-made Mouse Nae1/59kDa/Appbp1 siRNA oligo Duplex234664MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo696429Pre-made Cynomolgus/Rhesus macaque NAE1 siRNA oligo Duplex696429Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101086523Pre-made Cat/Feline NAE1 siRNA oligo Duplex101086523Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo610026Pre-made Dog/Canine NAE1/APPBP1 siRNA oligo Duplex610026Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo614491Pre-made Bovines/Cattle NAE1 siRNA oligo Duplex614491Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100065540Pre-made Equine/Horse NAE1 siRNA oligo Duplex100065540Equine/HorseIn-vitro grade; in-vivo gradeDetail


APPBP1/NAE1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-TA044-AbHumanAnti-Human APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-TA044-AbRatAnti-Rat APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-TA044-AbMouseAnti-Mouse APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-TA044-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-TA044-AbCat/FelineAnti-Cat/Feline APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-TA044-AbDog/CanineAnti-Dog/Canine APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-TA044-AbBovines/CattleAnti-Bovines/Cattle APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-TA044-AbEquine/HorseAnti-Equine/Horse APPBP1/NAE1 monoclonal antibodymabTherapeutics Target antibodyDetail


APPBP1/NAE1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-TA044-AgHumanHuman APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-rg-TA044-AgRatRat APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-mg-TA044-AgMouseMouse APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-TA044-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-felg-TA044-AgCat/FelineCat/Feline APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-cang-TA044-AgDog/CanineDog/Canine APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-TA044-AgBovines/CattleBovines/Cattle APPBP1/NAE1 recombinant proteinMammalian cellDetail
GM-Tg-equg-TA044-AgEquine/HorseEquine/Horse APPBP1/NAE1 recombinant proteinMammalian cellDetail