Explore APPBP1/NAE1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA044
|
| Target Name |
APPBP1/NAE1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8883
|
| Gene ID |
100065540 (Equus caballus), 101086523 (Felis catus), 234664 (Mus musculus), 610026 (Canis lupus familiaris)
614491 (Bos taurus), 696429 (Macaca mulatta), 84019 (Rattus norvegicus), 8883 (Homo sapiens)
|
| Target Alternative Names |
NAE1,Nae1,59kDa,Appbp1,APPBP1,RGD1563180,HPP1,ula-1,NEDFIH,A-116A10.1
|
| Uniprot Accession |
Q8VBW6,Q9Z1A5,Q13564
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000021954, ENSMUSG00000031878, ENSCAFG00845011147, ENSBTAG00000010132, ENSMMUG00000006752, ENSG00000159593
|
| Target Classification |
|
Pre-made viral vector of APPBP1/NAE1 cDNA Clones/ORF Plasmid
APPBP1/NAE1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8883 | Pre-made Human NAE1/HPP1/ula-1 siRNA oligo Duplex | 8883 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84019 | Pre-made Rat Nae1/Appbp1/RGD1563180 siRNA oligo Duplex | 84019 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo234664 | Pre-made Mouse Nae1/59kDa/Appbp1 siRNA oligo Duplex | 234664 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696429 | Pre-made Cynomolgus/Rhesus macaque NAE1 siRNA oligo Duplex | 696429 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086523 | Pre-made Cat/Feline NAE1 siRNA oligo Duplex | 101086523 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610026 | Pre-made Dog/Canine NAE1/APPBP1 siRNA oligo Duplex | 610026 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614491 | Pre-made Bovines/Cattle NAE1 siRNA oligo Duplex | 614491 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065540 | Pre-made Equine/Horse NAE1 siRNA oligo Duplex | 100065540 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
APPBP1/NAE1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA044-Ab | Human | Anti-Human APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA044-Ab | Rat | Anti-Rat APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA044-Ab | Mouse | Anti-Mouse APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA044-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA044-Ab | Cat/Feline | Anti-Cat/Feline APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA044-Ab | Dog/Canine | Anti-Dog/Canine APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA044-Ab | Bovines/Cattle | Anti-Bovines/Cattle APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA044-Ab | Equine/Horse | Anti-Equine/Horse APPBP1/NAE1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
APPBP1/NAE1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA044-Ag | Human | Human APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA044-Ag | Rat | Rat APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA044-Ag | Mouse | Mouse APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA044-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA044-Ag | Cat/Feline | Cat/Feline APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA044-Ag | Dog/Canine | Dog/Canine APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA044-Ag | Bovines/Cattle | Bovines/Cattle APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA044-Ag | Equine/Horse | Equine/Horse APPBP1/NAE1 recombinant protein | Mammalian cell | Detail |
