Explore Fibrinogen Alpha Chain/FGA gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016]
| Target ID |
GM-TA033
|
| Target Name |
Fibrinogen Alpha Chain/FGA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2243
|
| Gene ID |
100069763 (Equus caballus), 101092934 (Felis catus), 14161 (Mus musculus), 2243 (Homo sapiens)
361969 (Rattus norvegicus), 475473 (Canis lupus familiaris), 522039 (Bos taurus), 698244 (Macaca mulatta)
|
| Target Alternative Names |
FGA,Fga,Fib,Fib2,AMYLD2,Fba5e,Ac1873
|
| Uniprot Accession |
P14452,P14450,E9PV24,P02671,P06399,P68213,P02672,P68110
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Neonatal urinary tract infection, Ovarian cancer, Perinatal necrotizing enterocolitis
|
| Disease from KEGG |
Complement and coagulation cascades, Platelet activation
|
| Gene Ensembl |
ENSMUSG00000028001, ENSG00000171560, ENSCAFG00845009752, ENSBTAG00000001638, ENSMMUG00000021303
|
| Target Classification |
|
Fibrinogen Alpha Chain/FGA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2243 | Pre-made Human FGA/Fib2/AMYLD2 siRNA oligo Duplex | 2243 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361969 | Pre-made Rat Fga/Fba5e/Ac1873 siRNA oligo Duplex | 361969 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14161 | Pre-made Mouse Fga/Fib siRNA oligo Duplex | 14161 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698244 | Pre-made Cynomolgus/Rhesus macaque FGA siRNA oligo Duplex | 698244 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092934 | Pre-made Cat/Feline FGA siRNA oligo Duplex | 101092934 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475473 | Pre-made Dog/Canine FGA siRNA oligo Duplex | 475473 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo522039 | Pre-made Bovines/Cattle FGA siRNA oligo Duplex | 522039 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069763 | Pre-made Equine/Horse FGA siRNA oligo Duplex | 100069763 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Fibrinogen Alpha Chain/FGA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA033-Ab | Human | Anti-Human Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA033-Ab | Rat | Anti-Rat Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA033-Ab | Mouse | Anti-Mouse Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA033-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA033-Ab | Cat/Feline | Anti-Cat/Feline Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA033-Ab | Dog/Canine | Anti-Dog/Canine Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA033-Ab | Bovines/Cattle | Anti-Bovines/Cattle Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA033-Ab | Equine/Horse | Anti-Equine/Horse Fibrinogen Alpha Chain/FGA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Fibrinogen Alpha Chain/FGA VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA033-Ag | Human | Human Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA033-Ag | Rat | Rat Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA033-Ag | Mouse | Mouse Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA033-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA033-Ag | Cat/Feline | Cat/Feline Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA033-Ag | Dog/Canine | Dog/Canine Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA033-Ag | Bovines/Cattle | Bovines/Cattle Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA033-Ag | Equine/Horse | Equine/Horse Fibrinogen Alpha Chain/FGA VLP (virus-like particle) | HEK293 | Products Developing |
