Explore PSMA1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
| Target ID |
GM-TA030
|
| Target Name |
PSMA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5682
|
| Gene ID |
100056224 (Equus caballus), 101093640 (Felis catus), 26440 (Mus musculus), 29668 (Rattus norvegicus) 476867 (Canis lupus familiaris), 515503 (Bos taurus), 5682 (Homo sapiens), 701029 (Macaca mulatta)
|
| Target Alternative Names |
30 kDa prosomal protein (PROS-30),C2,HC2,HEL-S-275,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,NU,PROS30,PSMA1,Pros-30,Proteasome component C2,Proteasome nu chain,Proteasome subunit alpha type-1,Proteasome subunit alpha-6 (alpha-6),Psma1,alpha-type
|
| Uniprot Accession |
Q9R1P4,P18420,Q3T0X5,P25786
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000024086, ENSMUSG00000030751, ENSBTAG00000006564, ENSG00000129084, ENSMMUG00000016446
|
Pre-made viral vector of PSMA1 cDNA Clones/ORF Plasmid
PSMA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5682 | Pre-made Human PSMA1/NU/HC2 siRNA oligo Duplex | 5682 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29668 | Pre-made Rat Psma1 siRNA oligo Duplex | 29668 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26440 | Pre-made Mouse Psma1/C2/HC2 siRNA oligo Duplex | 26440 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701029 | Pre-made Cynomolgus/Rhesus macaque PSMA1 siRNA oligo Duplex | 701029 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093640 | Pre-made Cat/Feline PSMA1 siRNA oligo Duplex | 101093640 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476867 | Pre-made Dog/Canine PSMA1 siRNA oligo Duplex | 476867 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515503 | Pre-made Bovines/Cattle PSMA1 siRNA oligo Duplex | 515503 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056224 | Pre-made Equine/Horse PSMA1 siRNA oligo Duplex | 100056224 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PSMA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA030-Ab | Human | Anti-Human PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA030-Ab | Rat | Anti-Rat PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA030-Ab | Mouse | Anti-Mouse PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA030-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA030-Ab | Cat/Feline | Anti-Cat/Feline PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA030-Ab | Dog/Canine | Anti-Dog/Canine PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA030-Ab | Bovines/Cattle | Anti-Bovines/Cattle PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA030-Ab | Equine/Horse | Anti-Equine/Horse PSMA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PSMA1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA030-Ag | Human | Human PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA030-Ag | Rat | Rat PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA030-Ag | Mouse | Mouse PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA030-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA030-Ag | Cat/Feline | Cat/Feline PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA030-Ag | Dog/Canine | Dog/Canine PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA030-Ag | Bovines/Cattle | Bovines/Cattle PSMA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA030-Ag | Equine/Horse | Equine/Horse PSMA1 recombinant protein | Mammalian cell | Detail |