Explore CD41/Integrin alpha 2b/CD41a/ITGA2B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
| Target ID |
GM-TA029
|
| Target Name |
CD41/Integrin alpha 2b/CD41a/ITGA2B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3674
|
| Gene ID |
100009697 (Equus caballus), 101100930 (Felis catus), 16399 (Mus musculus), 3674 (Homo sapiens)
403789 (Canis lupus familiaris), 515011 (Bos taurus), 685269 (Rattus norvegicus), 714955 (Macaca mulatta)
|
| Target Alternative Names |
ITGA2B,Itga2b,CD41,CD41B,GpIIb,alphaIIb,GT,GT1,GTA,GP2B,HPA3,GPIIb,BDPLT2,BDPLT16,PPP1R93,GPIIB
|
| Uniprot Accession |
Q9QUM0,P08514
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Rap1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000019870, ENSMUSG00000034664, ENSG00000005961, ENSCAFG00845007943, ENSBTAG00000008165, ENSMMUG00000012659
|
| Target Classification |
|
CD41/Integrin alpha 2b/CD41a/ITGA2B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3674 | Pre-made Human ITGA2B/GT/GT1 siRNA oligo Duplex | 3674 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo685269 | Pre-made Rat Itga2b siRNA oligo Duplex | 685269 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16399 | Pre-made Mouse Itga2b/CD41/CD41B siRNA oligo Duplex | 16399 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714955 | Pre-made Cynomolgus/Rhesus macaque ITGA2B siRNA oligo Duplex | 714955 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100930 | Pre-made Cat/Feline ITGA2B siRNA oligo Duplex | 101100930 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403789 | Pre-made Dog/Canine ITGA2B/GPIIB siRNA oligo Duplex | 403789 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515011 | Pre-made Bovines/Cattle ITGA2B siRNA oligo Duplex | 515011 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009697 | Pre-made Equine/Horse ITGA2B siRNA oligo Duplex | 100009697 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD41/Integrin alpha 2b/CD41a/ITGA2B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA029-Ab | Human | Anti-Human CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA029-Ab | Rat | Anti-Rat CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA029-Ab | Mouse | Anti-Mouse CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA029-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA029-Ab | Cat/Feline | Anti-Cat/Feline CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA029-Ab | Dog/Canine | Anti-Dog/Canine CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA029-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA029-Ab | Equine/Horse | Anti-Equine/Horse CD41/Integrin alpha 2b/CD41a/ITGA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA029-Ag | Human | Human CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA029-Ag | Rat | Rat CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA029-Ag | Mouse | Mouse CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA029-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA029-Ag | Cat/Feline | Cat/Feline CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA029-Ag | Dog/Canine | Dog/Canine CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA029-Ag | Bovines/Cattle | Bovines/Cattle CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA029-Ag | Equine/Horse | Equine/Horse CD41/Integrin alpha 2b/CD41a/ITGA2B VLP (virus-like particle) | HEK293 | Products Developing |
