Explore GABBR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016]
| Target ID |
GM-TA028
|
| Target Name |
GABBR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2550
|
| Gene ID |
100147281 (Equus caballus), 101099637 (Felis catus), 2550 (Homo sapiens), 488340 (Canis lupus familiaris)
513785 (Bos taurus), 54393 (Mus musculus), 708987 (Macaca mulatta), 81657 (Rattus norvegicus)
|
| Target Alternative Names |
GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB1,GABABR1,GABAbR1,GABBR1,GABBR1-3,GB1,GPRC3A,Gabbr1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,NEDLC,bM573K1.1
|
| Uniprot Accession |
Q9UBS5,Q9WV18,Q9Z0U4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000009175, ENSG00000204681, ENSCAFG00845018375, ENSBTAG00000017239, ENSMUSG00000024462, ENSMMUG00000021483
|
| Target Classification |
GPCR
|
Pre-made viral vector of GABBR1 cDNA Clones/ORF Plasmid
GABBR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2550 | Pre-made Human GABBR1/GB1/NEDLC siRNA oligo Duplex | 2550 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81657 | Pre-made Rat Gabbr1 siRNA oligo Duplex | 81657 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54393 | Pre-made Mouse Gabbr1/GABAB1/GABAbR1 siRNA oligo Duplex | 54393 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708987 | Pre-made Cynomolgus/Rhesus macaque GABBR1 siRNA oligo Duplex | 708987 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099637 | Pre-made Cat/Feline GABBR1 siRNA oligo Duplex | 101099637 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488340 | Pre-made Dog/Canine GABBR1 siRNA oligo Duplex | 488340 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513785 | Pre-made Bovines/Cattle GABBR1 siRNA oligo Duplex | 513785 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147281 | Pre-made Equine/Horse GABBR1 siRNA oligo Duplex | 100147281 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABBR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA028-Ab | Human | Anti-Human GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA028-Ab | Rat | Anti-Rat GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA028-Ab | Mouse | Anti-Mouse GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA028-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA028-Ab | Cat/Feline | Anti-Cat/Feline GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA028-Ab | Dog/Canine | Anti-Dog/Canine GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA028-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA028-Ab | Equine/Horse | Anti-Equine/Horse GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABBR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA028-Ag | Human | Human GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA028-Ag | Rat | Rat GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA028-Ag | Mouse | Mouse GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA028-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA028-Ag | Cat/Feline | Cat/Feline GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA028-Ag | Dog/Canine | Dog/Canine GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA028-Ag | Bovines/Cattle | Bovines/Cattle GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA028-Ag | Equine/Horse | Equine/Horse GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
