Explore GABBR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016]
Target ID |
GM-TA028
|
Target Name |
GABBR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2550
|
Gene ID |
100147281 (Equus caballus), 101099637 (Felis catus), 2550 (Homo sapiens), 488340 (Canis lupus familiaris) 513785 (Bos taurus), 54393 (Mus musculus), 708987 (Macaca mulatta), 81657 (Rattus norvegicus)
|
Target Alternative Names |
GABBR1,Gabbr1,GB1,NEDLC,GPRC3A,GABABR1,GABBR1-3,GABAB1,GABAbR1,bM573K1.1
|
Uniprot Accession |
Q9UBS5,Q9WV18,Q9Z0U4
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, Morphine addiction
|
Gene Ensembl |
ENSECAG00000009175, ENSG00000204681, ENSCAFG00845018375, ENSBTAG00000017239, ENSMUSG00000024462, ENSMMUG00000021483
|
Target Classification |
GPCR
|
Pre-made viral vector of GABBR1 cDNA Clones/ORF Plasmid
GABBR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2550 | Pre-made Human GABBR1/GB1/NEDLC siRNA oligo Duplex | 2550 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo81657 | Pre-made Rat Gabbr1 siRNA oligo Duplex | 81657 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo54393 | Pre-made Mouse Gabbr1/GABAB1/GABAbR1 siRNA oligo Duplex | 54393 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo708987 | Pre-made Cynomolgus/Rhesus macaque GABBR1 siRNA oligo Duplex | 708987 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101099637 | Pre-made Cat/Feline GABBR1 siRNA oligo Duplex | 101099637 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo488340 | Pre-made Dog/Canine GABBR1 siRNA oligo Duplex | 488340 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo513785 | Pre-made Bovines/Cattle GABBR1 siRNA oligo Duplex | 513785 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100147281 | Pre-made Equine/Horse GABBR1 siRNA oligo Duplex | 100147281 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABBR1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-TA028-Ab | Human | Anti-Human GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-TA028-Ab | Rat | Anti-Rat GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-TA028-Ab | Mouse | Anti-Mouse GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-TA028-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-TA028-Ab | Cat/Feline | Anti-Cat/Feline GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-TA028-Ab | Dog/Canine | Anti-Dog/Canine GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-TA028-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-TA028-Ab | Equine/Horse | Anti-Equine/Horse GABBR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABBR1 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-TA028-Ag | Human | Human GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-TA028-Ag | Rat | Rat GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-TA028-Ag | Mouse | Mouse GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-TA028-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-TA028-Ag | Cat/Feline | Cat/Feline GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-TA028-Ag | Dog/Canine | Dog/Canine GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-TA028-Ag | Bovines/Cattle | Bovines/Cattle GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-TA028-Ag | Equine/Horse | Equine/Horse GABBR1 VLP (virus-like particle) | HEK293 | Products Developing |