Explore SCNN1A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
| Target ID |
GM-TA021
|
| Target Name |
SCNN1A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6337
|
| Gene ID |
100059623 (Equus caballus), 101091122 (Felis catus), 20276 (Mus musculus), 25122 (Rattus norvegicus)
282348 (Bos taurus), 403650 (Canis lupus familiaris), 6337 (Homo sapiens), 712476 (Macaca mulatta)
|
| Target Alternative Names |
SCNN1A,Scnn1a,ENaC,SCNEA,Scnn1,mENaC,ENaCA,BESC2,ENaCa,SCNN1,LIDLS3,PHA1B1,ENaCalpha
|
| Uniprot Accession |
Q61180,P37089,P55270,P37088
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Taste transduction, Aldosterone-regulated sodium reabsorption
|
| Gene Ensembl |
ENSECAG00000001443, ENSMUSG00000030340, ENSBTAG00000002631, ENSCAFG00845029331, ENSG00000111319, ENSMMUG00000020212
|
| Target Classification |
|
Pre-made viral vector of SCNN1A cDNA Clones/ORF Plasmid
SCNN1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6337 | Pre-made Human SCNN1A/BESC2/ENaCa siRNA oligo Duplex | 6337 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25122 | Pre-made Rat Scnn1a/ENaCA siRNA oligo Duplex | 25122 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20276 | Pre-made Mouse Scnn1a/ENaC/SCNEA siRNA oligo Duplex | 20276 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712476 | Pre-made Cynomolgus/Rhesus macaque SCNN1A siRNA oligo Duplex | 712476 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091122 | Pre-made Cat/Feline SCNN1A siRNA oligo Duplex | 101091122 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403650 | Pre-made Dog/Canine SCNN1A siRNA oligo Duplex | 403650 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282348 | Pre-made Bovines/Cattle SCNN1A siRNA oligo Duplex | 282348 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059623 | Pre-made Equine/Horse SCNN1A siRNA oligo Duplex | 100059623 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCNN1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA021-Ab | Human | Anti-Human SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA021-Ab | Rat | Anti-Rat SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA021-Ab | Mouse | Anti-Mouse SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA021-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA021-Ab | Cat/Feline | Anti-Cat/Feline SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA021-Ab | Dog/Canine | Anti-Dog/Canine SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA021-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA021-Ab | Equine/Horse | Anti-Equine/Horse SCNN1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SCNN1A VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA021-Ag | Human | Human SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA021-Ag | Rat | Rat SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA021-Ag | Mouse | Mouse SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA021-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA021-Ag | Cat/Feline | Cat/Feline SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA021-Ag | Dog/Canine | Dog/Canine SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA021-Ag | Bovines/Cattle | Bovines/Cattle SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA021-Ag | Equine/Horse | Equine/Horse SCNN1A VLP (virus-like particle) | HEK293 | Products Developing |
