Explore Inhibin/INHBA gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016]
| Target ID |
GM-TA010
|
| Target Name |
Inhibin/INHBA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3624
|
| Gene ID |
100034076 (Equus caballus), 16323 (Mus musculus), 281867 (Bos taurus), 29200 (Rattus norvegicus) 3624 (Homo sapiens), 483245 (Canis lupus familiaris), 493853 (Felis catus), 702734 (Macaca mulatta)
|
| Target Alternative Names |
Activin beta-A chain,EDF,Erythroid differentiation protein (EDF),FRP,INHBA,Inhba,Inhibin,Inhibin beta A chain
|
| Uniprot Accession |
P55102,Q04998,P07995,P18331,P08476,Q6X2S4
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells
|
| Gene Ensembl |
ENSMUSG00000041324, ENSBTAG00000056438, ENSG00000122641, ENSCAFG00845018632, ENSMMUG00000061466
|
Pre-made viral vector of Inhibin/INHBA cDNA Clones/ORF Plasmid
Inhibin/INHBA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3624 | Pre-made Human INHBA/EDF/FRP siRNA oligo Duplex | 3624 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29200 | Pre-made Rat Inhba siRNA oligo Duplex | 29200 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16323 | Pre-made Mouse Inhba siRNA oligo Duplex | 16323 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702734 | Pre-made Cynomolgus/Rhesus macaque INHBA siRNA oligo Duplex | 702734 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493853 | Pre-made Cat/Feline INHBA siRNA oligo Duplex | 493853 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483245 | Pre-made Dog/Canine INHBA siRNA oligo Duplex | 483245 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281867 | Pre-made Bovines/Cattle INHBA siRNA oligo Duplex | 281867 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034076 | Pre-made Equine/Horse INHBA siRNA oligo Duplex | 100034076 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Inhibin/INHBA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA010-Ab | Human | Anti-Human Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA010-Ab | Rat | Anti-Rat Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA010-Ab | Mouse | Anti-Mouse Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA010-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA010-Ab | Cat/Feline | Anti-Cat/Feline Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA010-Ab | Dog/Canine | Anti-Dog/Canine Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA010-Ab | Bovines/Cattle | Anti-Bovines/Cattle Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA010-Ab | Equine/Horse | Anti-Equine/Horse Inhibin/INHBA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Inhibin/INHBA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA010-Ag | Human | Human Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA010-Ag | Rat | Rat Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA010-Ag | Mouse | Mouse Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA010-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA010-Ag | Cat/Feline | Cat/Feline Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA010-Ag | Dog/Canine | Dog/Canine Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA010-Ag | Bovines/Cattle | Bovines/Cattle Inhibin/INHBA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA010-Ag | Equine/Horse | Equine/Horse Inhibin/INHBA recombinant protein | Mammalian cell | Detail |