Explore IL17RA/IL-17RA/CD217 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
| Target ID |
GM-TA009
|
| Target Name |
IL17RA/IL-17RA/CD217
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23765
|
| Gene ID |
100055511 (Equus caballus), 101095588 (Felis catus), 16172 (Mus musculus), 23765 (Homo sapiens)
312679 (Rattus norvegicus), 486759 (Canis lupus familiaris), 525040 (Bos taurus), 709005 (Macaca mulatta)
|
| Target Alternative Names |
CANDF5,CD217,CDw217,Cdw217,IL-17 receptor A,IL-17RA,IL17R,IL17RA,IMD51,Il17r,Il17ra,Interleukin-17 receptor A,VDw217,hIL-17R
|
| Uniprot Accession |
Q60943,Q96F46
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000017077, ENSMUSG00000002897, ENSG00000177663, ENSCAFG00845030604, ENSBTAG00000011067, ENSMMUG00000022222
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL17RA/IL-17RA/CD217 cDNA Clones/ORF Plasmid
IL17RA/IL-17RA/CD217 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23765 | Pre-made Human IL17RA/CD217/IL17R siRNA oligo Duplex | 23765 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312679 | Pre-made Rat Il17ra/Il17r siRNA oligo Duplex | 312679 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16172 | Pre-made Mouse Il17ra/Il17r/Cdw217 siRNA oligo Duplex | 16172 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709005 | Pre-made Cynomolgus/Rhesus macaque IL17RA siRNA oligo Duplex | 709005 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095588 | Pre-made Cat/Feline IL17RA siRNA oligo Duplex | 101095588 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486759 | Pre-made Dog/Canine IL17RA siRNA oligo Duplex | 486759 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525040 | Pre-made Bovines/Cattle IL17RA siRNA oligo Duplex | 525040 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055511 | Pre-made Equine/Horse IL17RA siRNA oligo Duplex | 100055511 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL17RA/IL-17RA/CD217 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA009-Ab | Human | Anti-Human IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-TA009-Ab | Rat | Anti-Rat IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-TA009-Ab | Mouse | Anti-Mouse IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-TA009-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-TA009-Ab | Cat/Feline | Anti-Cat/Feline IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-TA009-Ab | Dog/Canine | Anti-Dog/Canine IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-TA009-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-TA009-Ab | Equine/Horse | Anti-Equine/Horse IL17RA/IL-17RA/CD217 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL17RA/IL-17RA/CD217 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA009-Ag | Human | Human IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA009-Ag | Rat | Rat IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA009-Ag | Mouse | Mouse IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA009-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA009-Ag | Cat/Feline | Cat/Feline IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA009-Ag | Dog/Canine | Dog/Canine IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA009-Ag | Bovines/Cattle | Bovines/Cattle IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA009-Ag | Equine/Horse | Equine/Horse IL17RA/IL-17RA/CD217 VLP (virus-like particle) | HEK293 | Products Developing |
