Explore NMBR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
| Target ID |
GM-TA003
|
| Target Name |
NMBR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4829
|
| Gene ID |
100060776 (Equus caballus), 101089107 (Felis catus), 18101 (Mus musculus), 25264 (Rattus norvegicus)
4829 (Homo sapiens), 539776 (Bos taurus), 574262 (Macaca mulatta), 611644 (Canis lupus familiaris)
|
| Target Alternative Names |
BB1,BB1R,BRS1,Epididymis tissue protein Li 185a,NMB-R,NMBR,Neuromedin-B receptor,Neuromedin-B-preferring bombesin receptor,Nmbr
|
| Uniprot Accession |
O54799,P24053,P28336
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000015557, ENSMUSG00000019865, ENSG00000135577, ENSBTAG00000043954, ENSMMUG00000054902, ENSCAFG00845010954
|
| Target Classification |
GPCR
|
NMBR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4829 | Pre-made Human NMBR/BB1/BB1R siRNA oligo Duplex | 4829 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25264 | Pre-made Rat Nmbr/NMB-R siRNA oligo Duplex | 25264 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18101 | Pre-made Mouse Nmbr siRNA oligo Duplex | 18101 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574262 | Pre-made Cynomolgus/Rhesus macaque NMBR siRNA oligo Duplex | 574262 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089107 | Pre-made Cat/Feline NMBR siRNA oligo Duplex | 101089107 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611644 | Pre-made Dog/Canine NMBR siRNA oligo Duplex | 611644 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539776 | Pre-made Bovines/Cattle NMBR siRNA oligo Duplex | 539776 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060776 | Pre-made Equine/Horse NMBR siRNA oligo Duplex | 100060776 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NMBR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA003-Ab | Human | Anti-Human NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA003-Ab | Rat | Anti-Rat NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA003-Ab | Mouse | Anti-Mouse NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA003-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA003-Ab | Cat/Feline | Anti-Cat/Feline NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA003-Ab | Dog/Canine | Anti-Dog/Canine NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA003-Ab | Bovines/Cattle | Anti-Bovines/Cattle NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA003-Ab | Equine/Horse | Anti-Equine/Horse NMBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NMBR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA003-Ag | Human | Human NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA003-Ag | Rat | Rat NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA003-Ag | Mouse | Mouse NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA003-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA003-Ag | Cat/Feline | Cat/Feline NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA003-Ag | Dog/Canine | Dog/Canine NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA003-Ag | Bovines/Cattle | Bovines/Cattle NMBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA003-Ag | Equine/Horse | Equine/Horse NMBR VLP (virus-like particle) | HEK293 | Products Developing |
