Explore BMX gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
| Target ID |
GM-T99990
|
| Target Name |
BMX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
660
|
| Gene ID |
100051025 (Equus caballus), 101095795 (Felis catus), 12169 (Mus musculus), 367786 (Rattus norvegicus)
491750 (Canis lupus familiaris), 531514 (Bos taurus), 660 (Homo sapiens), 712722 (Macaca mulatta)
|
| Target Alternative Names |
BMX,Bmx,Etk,Tyro8,Etk/Bmx,RGD1565643,ETK,PSCTK2,PSCTK3
|
| Uniprot Accession |
P97504,P51813
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000016017, ENSMUSG00000031377, ENSCAFG00845029748, ENSBTAG00000000377, ENSG00000102010, ENSMMUG00000014047
|
| Target Classification |
Kinase
|
Pre-made viral vector of BMX cDNA Clones/ORF Plasmid
BMX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo660 | Pre-made Human BMX/ETK/PSCTK2 siRNA oligo Duplex | 660 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo367786 | Pre-made Rat Bmx/RGD1565643 siRNA oligo Duplex | 367786 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12169 | Pre-made Mouse Bmx/Etk/Tyro8 siRNA oligo Duplex | 12169 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712722 | Pre-made Cynomolgus/Rhesus macaque BMX siRNA oligo Duplex | 712722 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095795 | Pre-made Cat/Feline BMX siRNA oligo Duplex | 101095795 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491750 | Pre-made Dog/Canine BMX siRNA oligo Duplex | 491750 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo531514 | Pre-made Bovines/Cattle BMX siRNA oligo Duplex | 531514 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051025 | Pre-made Equine/Horse BMX siRNA oligo Duplex | 100051025 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99990-Ab | Human | Anti-Human BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99990-Ab | Rat | Anti-Rat BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99990-Ab | Mouse | Anti-Mouse BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99990-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99990-Ab | Cat/Feline | Anti-Cat/Feline BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99990-Ab | Dog/Canine | Anti-Dog/Canine BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99990-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99990-Ab | Equine/Horse | Anti-Equine/Horse BMX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
BMX VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99990-Ag | Human | Human BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99990-Ag | Rat | Rat BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99990-Ag | Mouse | Mouse BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99990-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99990-Ag | Cat/Feline | Cat/Feline BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99990-Ag | Dog/Canine | Dog/Canine BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99990-Ag | Bovines/Cattle | Bovines/Cattle BMX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99990-Ag | Equine/Horse | Equine/Horse BMX VLP (virus-like particle) | HEK293 | Products Developing |
