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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T99954
|
| Target Name |
PTGIR
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5739
|
| Gene ID |
100071157 (Equus caballus), 101100609 (Felis catus), 19222 (Mus musculus), 292661 (Rattus norvegicus) 484429 (Canis lupus familiaris), 520278 (Bos taurus), 5739 (Homo sapiens), 716546 (Macaca mulatta)
|
| Target Alternative Names |
IP,PGI2,PGI2 receptor),PRIPR,PTGIR,Prostacyclin receptor,Prostaglandin I2 receptor (PGI receptor,Prostanoid IP receptor,Ptgir
|
| Uniprot Accession |
P43252,P43253,P79393,P43119
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Platelet activation
|
| Gene Ensembl |
ENSECAG00000023626, ENSMUSG00000043017, ENSCAFG00845004281, ENSBTAG00000014585, ENSG00000160013, ENSMMUG00000017922
|
| Target Classification |
GPCR
|
Pre-made viral vector of PTGIR cDNA Clones/ORF Plasmid
PTGIR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5739 | Pre-made Human PTGIR/IP/PRIPR siRNA oligo Duplex | 5739 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292661 | Pre-made Rat Ptgir siRNA oligo Duplex | 292661 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19222 | Pre-made Mouse Ptgir/IP/PGI2 siRNA oligo Duplex | 19222 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716546 | Pre-made Cynomolgus/Rhesus macaque PTGIR siRNA oligo Duplex | 716546 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100609 | Pre-made Cat/Feline PTGIR siRNA oligo Duplex | 101100609 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484429 | Pre-made Dog/Canine PTGIR siRNA oligo Duplex | 484429 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520278 | Pre-made Bovines/Cattle PTGIR siRNA oligo Duplex | 520278 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071157 | Pre-made Equine/Horse PTGIR siRNA oligo Duplex | 100071157 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTGIR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99954-Ab | Human | Anti-Human PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99954-Ab | Rat | Anti-Rat PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99954-Ab | Mouse | Anti-Mouse PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99954-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99954-Ab | Cat/Feline | Anti-Cat/Feline PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99954-Ab | Dog/Canine | Anti-Dog/Canine PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99954-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99954-Ab | Equine/Horse | Anti-Equine/Horse PTGIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTGIR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99954-Ag | Human | Human PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99954-Ag | Rat | Rat PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99954-Ag | Mouse | Mouse PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99954-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99954-Ag | Cat/Feline | Cat/Feline PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99954-Ag | Dog/Canine | Dog/Canine PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99954-Ag | Bovines/Cattle | Bovines/Cattle PTGIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99954-Ag | Equine/Horse | Equine/Horse PTGIR VLP (virus-like particle) | HEK293 | Products Developing |