Explore BCHE gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T99799
|
| Target Name |
BCHE
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
590
|
| Gene ID |
100033901 (Equus caballus), 12038 (Mus musculus), 488143 (Canis lupus familiaris), 493960 (Felis catus)
534616 (Bos taurus), 590 (Homo sapiens), 65036 (Rattus norvegicus), 700484 (Macaca mulatta)
|
| Target Alternative Names |
Acylcholine acylhydrolase,BCHE,BCHED,Bche,Butyrylcholine esterase,C730038G20Rik,CHE1,CHE2,Choline esterase II,Cholinesterase,E1,EQ-BCHE,Pseudocholinesterase
|
| Uniprot Accession |
P81908,Q03311,P32750,O62760,P32749,P06276,P32751
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer, Neurological effects, OP toxicity
|
| Gene Ensembl |
ENSECAG00000000240, ENSMUSG00000027792, ENSCAFG00845018401, ENSBTAG00000011139, ENSG00000114200, ENSMMUG00000003742
|
Pre-made viral vector of BCHE cDNA Clones/ORF Plasmid
BCHE siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo590 | Pre-made Human BCHE/E1/CHE1 siRNA oligo Duplex | 590 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65036 | Pre-made Rat Bche siRNA oligo Duplex | 65036 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12038 | Pre-made Mouse Bche/C730038G20Rik siRNA oligo Duplex | 12038 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700484 | Pre-made Cynomolgus/Rhesus macaque BCHE siRNA oligo Duplex | 700484 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493960 | Pre-made Cat/Feline BCHE siRNA oligo Duplex | 493960 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488143 | Pre-made Dog/Canine BCHE siRNA oligo Duplex | 488143 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534616 | Pre-made Bovines/Cattle BCHE siRNA oligo Duplex | 534616 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033901 | Pre-made Equine/Horse BCHE/EQ-BCHE siRNA oligo Duplex | 100033901 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BCHE antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99799-Ab | Human | Anti-Human BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99799-Ab | Rat | Anti-Rat BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99799-Ab | Mouse | Anti-Mouse BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99799-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99799-Ab | Cat/Feline | Anti-Cat/Feline BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99799-Ab | Dog/Canine | Anti-Dog/Canine BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99799-Ab | Bovines/Cattle | Anti-Bovines/Cattle BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99799-Ab | Equine/Horse | Anti-Equine/Horse BCHE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
BCHE VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99799-Ag | Human | Human BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99799-Ag | Rat | Rat BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99799-Ag | Mouse | Mouse BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99799-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99799-Ag | Cat/Feline | Cat/Feline BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99799-Ag | Dog/Canine | Dog/Canine BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99799-Ag | Bovines/Cattle | Bovines/Cattle BCHE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99799-Ag | Equine/Horse | Equine/Horse BCHE VLP (virus-like particle) | HEK293 | Products Developing |
