Explore GRM5/mGluR5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
| Target ID |
GM-T99347
|
| Target Name |
GRM5/mGluR5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2915
|
| Gene ID |
100060364 (Equus caballus), 100336861 (Bos taurus), 101091895 (Felis catus), 108071 (Mus musculus)
24418 (Rattus norvegicus), 2915 (Homo sapiens), 485146 (Canis lupus familiaris), 705445 (Macaca mulatta)
|
| Target Alternative Names |
6430542K11Rik,GPRC1E,GRM5,Glu5R,Gprc1e,Grm5,MGLUR5,Metabotropic glutamate receptor 5,PPP1R86,mGlu5,mGluR5,mGluR5b,mGlur5
|
| Uniprot Accession |
Q3UVX5,P31424,P41594
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Long-term potentiation, Glutamatergic synapse, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000018967, ENSBTAG00000048061, ENSMUSG00000049583, ENSG00000168959, ENSCAFG00845025940, ENSMMUG00000010184
|
| Target Classification |
GPCR
|
GRM5/mGluR5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2915 | Pre-made Human GRM5/mGlu5/GPRC1E siRNA oligo Duplex | 2915 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24418 | Pre-made Rat Grm5/mGluR5/mGlur5 siRNA oligo Duplex | 24418 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo108071 | Pre-made Mouse Grm5/Glu5R/Gprc1e siRNA oligo Duplex | 108071 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705445 | Pre-made Cynomolgus/Rhesus macaque GRM5 siRNA oligo Duplex | 705445 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091895 | Pre-made Cat/Feline GRM5 siRNA oligo Duplex | 101091895 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485146 | Pre-made Dog/Canine GRM5 siRNA oligo Duplex | 485146 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336861 | Pre-made Bovines/Cattle GRM5 siRNA oligo Duplex | 100336861 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060364 | Pre-made Equine/Horse GRM5 siRNA oligo Duplex | 100060364 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRM5/mGluR5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99347-Ab | Human | Anti-Human GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99347-Ab | Rat | Anti-Rat GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99347-Ab | Mouse | Anti-Mouse GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99347-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99347-Ab | Cat/Feline | Anti-Cat/Feline GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99347-Ab | Dog/Canine | Anti-Dog/Canine GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99347-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99347-Ab | Equine/Horse | Anti-Equine/Horse GRM5/mGluR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GRM5/mGluR5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99347-Ag | Human | Human GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99347-Ag | Rat | Rat GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99347-Ag | Mouse | Mouse GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99347-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99347-Ag | Cat/Feline | Cat/Feline GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99347-Ag | Dog/Canine | Dog/Canine GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99347-Ag | Bovines/Cattle | Bovines/Cattle GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99347-Ag | Equine/Horse | Equine/Horse GRM5/mGluR5 VLP (virus-like particle) | HEK293 | Products Developing |
