Explore RIPK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T99340
|
| Target Name |
RIPK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8737
|
| Gene ID |
100058015 (Equus caballus), 101087663 (Felis catus), 102152063 (Canis lupus familiaris), 19766 (Mus musculus)
306886 (Rattus norvegicus), 504727 (Bos taurus), 708013 (Macaca mulatta), 8737 (Homo sapiens)
|
| Target Alternative Names |
AIEFL,Cell death protein RIP,D330015H01Rik,IMD57,RIP,RIP-1,RIP1,RIPK1,Receptor-interacting protein 1 (RIP-1),Receptor-interacting serine/threonine-protein kinase 1,Rinp,Rip1,Ripk1
|
| Uniprot Accession |
Q60855,Q13546
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NF-kappa B signaling pathway, Apoptosis, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, TNF signaling pathway, Alcoholic liver disease, Pathogenic Escherichia coli infection, Hepatitis C, Human cytomegalovirus infection, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000010293, ENSMUSG00000021408, ENSBTAG00000006378, ENSMMUG00000008485, ENSG00000137275
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of RIPK1 cDNA Clones/ORF Plasmid
RIPK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8737 | Pre-made Human RIPK1/RIP/RIP1 siRNA oligo Duplex | 8737 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306886 | Pre-made Rat Ripk1 siRNA oligo Duplex | 306886 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19766 | Pre-made Mouse Ripk1/RIP/Rinp siRNA oligo Duplex | 19766 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708013 | Pre-made Cynomolgus/Rhesus macaque RIPK1 siRNA oligo Duplex | 708013 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087663 | Pre-made Cat/Feline RIPK1 siRNA oligo Duplex | 101087663 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102152063 | Pre-made Dog/Canine RIPK1 siRNA oligo Duplex | 102152063 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504727 | Pre-made Bovines/Cattle RIPK1 siRNA oligo Duplex | 504727 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058015 | Pre-made Equine/Horse RIPK1 siRNA oligo Duplex | 100058015 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RIPK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99340-Ab | Human | Anti-Human RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99340-Ab | Rat | Anti-Rat RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99340-Ab | Mouse | Anti-Mouse RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99340-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99340-Ab | Cat/Feline | Anti-Cat/Feline RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99340-Ab | Dog/Canine | Anti-Dog/Canine RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99340-Ab | Bovines/Cattle | Anti-Bovines/Cattle RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99340-Ab | Equine/Horse | Anti-Equine/Horse RIPK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RIPK1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99340-Ag | Human | Human RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99340-Ag | Rat | Rat RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99340-Ag | Mouse | Mouse RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99340-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99340-Ag | Cat/Feline | Cat/Feline RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99340-Ag | Dog/Canine | Dog/Canine RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99340-Ag | Bovines/Cattle | Bovines/Cattle RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99340-Ag | Equine/Horse | Equine/Horse RIPK1 VLP (virus-like particle) | HEK293 | Products Developing |
