Explore TMEM173/STING/STING1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
| Target ID |
GM-T99338
|
| Target Name |
TMEM173/STING/STING1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
340061
|
| Gene ID |
100062046 (Equus caballus), 101090737 (Felis catus), 340061 (Homo sapiens), 498840 (Rattus norvegicus)
533661 (Bos taurus), 606815 (Canis lupus familiaris), 694353 (Macaca mulatta), 72512 (Mus musculus)
|
| Target Alternative Names |
2610307O08Rik,ECSCR,ECSM2,ERIS,Endoplasmic reticulum interferon stimulator (ERIS),MITA,MPYS,Mediator of IRF3 activation (hMITA),Mita,NET23,RGD1562552,SAVI,STING,STING-beta,STING1,Stimulator of interferon genes protein,Sting1,TMEM173,Tmem173,Transmembrane protein 173,hMITA,hSTING,rSTING
|
| Uniprot Accession |
Q86WV6,F1M391,Q2KI99,P0C8R9,Q3TBT3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Human cytomegalovirus infection
|
| Gene Ensembl |
ENSECAG00000017396, ENSG00000184584, ENSBTAG00000002296, ENSCAFG00845000875, ENSMMUG00000012048, ENSMUSG00000024349
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of TMEM173/STING/STING1 cDNA Clones/ORF Plasmid
TMEM173/STING/STING1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo340061 | Pre-made Human STING1/ERIS/MITA siRNA oligo Duplex | 340061 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498840 | Pre-made Rat Sting1/rSTING/Tmem173 siRNA oligo Duplex | 498840 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72512 | Pre-made Mouse Sting1/ERIS/MPYS siRNA oligo Duplex | 72512 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694353 | Pre-made Cynomolgus/Rhesus macaque STING1/STING/TMEM173 siRNA oligo Duplex | 694353 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090737 | Pre-made Cat/Feline STING1/STING/TMEM173 siRNA oligo Duplex | 101090737 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606815 | Pre-made Dog/Canine STING1/ECSCR/ECSM2 siRNA oligo Duplex | 606815 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533661 | Pre-made Bovines/Cattle STING1/STING/TMEM173 siRNA oligo Duplex | 533661 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062046 | Pre-made Equine/Horse STING1/TMEM173 siRNA oligo Duplex | 100062046 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TMEM173/STING/STING1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99338-Ab | Human | Anti-Human TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99338-Ab | Rat | Anti-Rat TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99338-Ab | Mouse | Anti-Mouse TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99338-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99338-Ab | Cat/Feline | Anti-Cat/Feline TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99338-Ab | Dog/Canine | Anti-Dog/Canine TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99338-Ab | Bovines/Cattle | Anti-Bovines/Cattle TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99338-Ab | Equine/Horse | Anti-Equine/Horse TMEM173/STING/STING1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TMEM173/STING/STING1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99338-Ag | Human | Human TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99338-Ag | Rat | Rat TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99338-Ag | Mouse | Mouse TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99338-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99338-Ag | Cat/Feline | Cat/Feline TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99338-Ag | Dog/Canine | Dog/Canine TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99338-Ag | Bovines/Cattle | Bovines/Cattle TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99338-Ag | Equine/Horse | Equine/Horse TMEM173/STING/STING1 VLP (virus-like particle) | HEK293 | Products Developing |
