Explore SLC10A1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
| Target ID |
GM-T99189
|
| Target Name |
SLC10A1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6554
|
| Gene ID |
100064290 (Equus caballus), 101080544 (Felis catus), 20493 (Mus musculus), 24777 (Rattus norvegicus)
480372 (Canis lupus familiaris), 532890 (Bos taurus), 6554 (Homo sapiens), 712925 (Macaca mulatta)
|
| Target Alternative Names |
Cell growth-inhibiting gene 29 protein,FHCA2,Hepatic sodium/bile acid cotransporter,NTCP,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Ntcp,Ntcp1,SBACT,SLC10A1,Slc10a1,Sodium/taurocholate cotransporting polypeptide (NTCP),Solute carrier family 10 member 1 (SLC10A1)
|
| Uniprot Accession |
O08705,P26435,Q14973
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Bile secretion, Hepatitis B
|
| Gene Ensembl |
ENSECAG00000014920, ENSMUSG00000021135, ENSCAFG00845004225, ENSBTAG00000001881, ENSG00000100652, ENSMMUG00000022409
|
Pre-made viral vector of SLC10A1 cDNA Clones/ORF Plasmid
SLC10A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6554 | Pre-made Human SLC10A1/NTCP/FHCA2 siRNA oligo Duplex | 6554 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24777 | Pre-made Rat Slc10a1/Ntcp/Ntcp1 siRNA oligo Duplex | 24777 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20493 | Pre-made Mouse Slc10a1/Ntcp siRNA oligo Duplex | 20493 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712925 | Pre-made Cynomolgus/Rhesus macaque SLC10A1/Ntcp siRNA oligo Duplex | 712925 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080544 | Pre-made Cat/Feline SLC10A1 siRNA oligo Duplex | 101080544 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480372 | Pre-made Dog/Canine SLC10A1 siRNA oligo Duplex | 480372 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532890 | Pre-made Bovines/Cattle SLC10A1 siRNA oligo Duplex | 532890 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064290 | Pre-made Equine/Horse SLC10A1 siRNA oligo Duplex | 100064290 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SLC10A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99189-Ab | Human | Anti-Human SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99189-Ab | Rat | Anti-Rat SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99189-Ab | Mouse | Anti-Mouse SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99189-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99189-Ab | Cat/Feline | Anti-Cat/Feline SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99189-Ab | Dog/Canine | Anti-Dog/Canine SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99189-Ab | Bovines/Cattle | Anti-Bovines/Cattle SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99189-Ab | Equine/Horse | Anti-Equine/Horse SLC10A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SLC10A1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99189-Ag | Human | Human SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99189-Ag | Rat | Rat SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99189-Ag | Mouse | Mouse SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99189-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99189-Ag | Cat/Feline | Cat/Feline SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99189-Ag | Dog/Canine | Dog/Canine SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99189-Ag | Bovines/Cattle | Bovines/Cattle SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99189-Ag | Equine/Horse | Equine/Horse SLC10A1 VLP (virus-like particle) | HEK293 | Products Developing |
