Explore G-CSFR/CSF3R/CD114/G-CSF-R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
| Target ID |
GM-T98913
|
| Target Name |
G-CSFR/CSF3R/CD114/G-CSF-R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1441
|
| Gene ID |
100069253 (Equus caballus), 101089787 (Felis catus), 12986 (Mus musculus), 132344945 (Bos taurus) 1441 (Homo sapiens), 298518 (Rattus norvegicus), 607605 (Canis lupus familiaris), 713485 (Macaca mulatta)
|
| Target Alternative Names |
CD114,CSF3R,Cd114,Csf3r,Csfgr,G-CSF receptor,G-CSF-R,G-CSFR,GCSFR,Granulocyte colony-stimulating factor receptor,SCN7
|
| Uniprot Accession |
P40223,Q99062
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000013457, ENSMUSG00000028859, ENSBTAG00000013334, ENSG00000119535, ENSCAFG00845030757, ENSMMUG00000020434
|
| Target Classification |
Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
G-CSFR/CSF3R/CD114/G-CSF-R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1441 | Pre-made Human CSF3R/SCN7/CD114 siRNA oligo Duplex | 1441 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298518 | Pre-made Rat Csf3r siRNA oligo Duplex | 298518 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12986 | Pre-made Mouse Csf3r/Cd114/Csfgr siRNA oligo Duplex | 12986 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713485 | Pre-made Cynomolgus/Rhesus macaque CSF3R siRNA oligo Duplex | 713485 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089787 | Pre-made Cat/Feline CSF3R siRNA oligo Duplex | 101089787 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607605 | Pre-made Dog/Canine CSF3R siRNA oligo Duplex | 607605 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo132344945 | Pre-made Bovines/Cattle CSF3R siRNA oligo Duplex | 132344945 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069253 | Pre-made Equine/Horse CSF3R siRNA oligo Duplex | 100069253 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
G-CSFR/CSF3R/CD114/G-CSF-R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98913-Ab | Human | Anti-Human G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98913-Ab | Rat | Anti-Rat G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98913-Ab | Mouse | Anti-Mouse G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98913-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98913-Ab | Cat/Feline | Anti-Cat/Feline G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98913-Ab | Dog/Canine | Anti-Dog/Canine G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98913-Ab | Bovines/Cattle | Anti-Bovines/Cattle G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98913-Ab | Equine/Horse | Anti-Equine/Horse G-CSFR/CSF3R/CD114/G-CSF-R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98913-Ag | Human | Human G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T98913-Ag | Rat | Rat G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T98913-Ag | Mouse | Mouse G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T98913-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T98913-Ag | Cat/Feline | Cat/Feline G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T98913-Ag | Dog/Canine | Dog/Canine G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T98913-Ag | Bovines/Cattle | Bovines/Cattle G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T98913-Ag | Equine/Horse | Equine/Horse G-CSFR/CSF3R/CD114/G-CSF-R VLP (virus-like particle) | HEK293 | Products Developing |