Explore ANGPTL4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
| Target ID |
GM-T98635
|
| Target Name |
ANGPTL4
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
51129
|
| Gene ID |
100067036 (Equus caballus), 101090747 (Felis catus), 362850 (Rattus norvegicus), 476724 (Canis lupus familiaris) 509963 (Bos taurus), 51129 (Homo sapiens), 57875 (Mus musculus), 711693 (Macaca mulatta)
|
| Target Alternative Names |
ANGPTL4,ARP4,Angiopoietin-like protein 4,Angiopoietin-related protein 4,Angptl4,Arp4,Bk89,FIAF,Fiaf,HARP,HFARP,Hepatic fibrinogen/angiopoietin-related protein (HFARP),Hfarp,NL2,Ng27,PGAR,Pgar,Pgarg,Pp1158,TGQTL,UNQ171,pp1158
|
| Uniprot Accession |
Q6TMA8,Q2KJ51,Q9BY76,Q9Z1P8
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PPAR signaling pathway, Cholesterol metabolism
|
| Gene Ensembl |
ENSECAG00000018927, ENSCAFG00845006010, ENSBTAG00000002473, ENSG00000167772, ENSMUSG00000002289, ENSMMUG00000000698
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ANGPTL4 cDNA Clones/ORF Plasmid
ANGPTL4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51129 | Pre-made Human ANGPTL4/NL2/ARP4 siRNA oligo Duplex | 51129 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362850 | Pre-made Rat Angptl4 siRNA oligo Duplex | 362850 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57875 | Pre-made Mouse Angptl4/Arp4/Bk89 siRNA oligo Duplex | 57875 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711693 | Pre-made Cynomolgus/Rhesus macaque ANGPTL4 siRNA oligo Duplex | 711693 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090747 | Pre-made Cat/Feline ANGPTL4 siRNA oligo Duplex | 101090747 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476724 | Pre-made Dog/Canine ANGPTL4 siRNA oligo Duplex | 476724 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509963 | Pre-made Bovines/Cattle ANGPTL4 siRNA oligo Duplex | 509963 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067036 | Pre-made Equine/Horse ANGPTL4 siRNA oligo Duplex | 100067036 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ANGPTL4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98635-Ab | Human | Anti-Human ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98635-Ab | Rat | Anti-Rat ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98635-Ab | Mouse | Anti-Mouse ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98635-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98635-Ab | Cat/Feline | Anti-Cat/Feline ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98635-Ab | Dog/Canine | Anti-Dog/Canine ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98635-Ab | Bovines/Cattle | Anti-Bovines/Cattle ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98635-Ab | Equine/Horse | Anti-Equine/Horse ANGPTL4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ANGPTL4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98635-Ag | Human | Human ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98635-Ag | Rat | Rat ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98635-Ag | Mouse | Mouse ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98635-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98635-Ag | Cat/Feline | Cat/Feline ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98635-Ag | Dog/Canine | Dog/Canine ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98635-Ag | Bovines/Cattle | Bovines/Cattle ANGPTL4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98635-Ag | Equine/Horse | Equine/Horse ANGPTL4 recombinant protein | Mammalian cell | Detail |