Explore Tie1/TIE1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
| Target ID |
GM-T98539
|
| Target Name |
Tie1/TIE1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7075
|
| Gene ID |
100066563 (Equus caballus), 101080986 (Felis catus), 21846 (Mus musculus), 280941 (Bos taurus)
482535 (Canis lupus familiaris), 702208 (Macaca mulatta), 7075 (Homo sapiens), 89806 (Rattus norvegicus)
|
| Target Alternative Names |
D430008P04Rik,JTK14,LMPHM11,TIE,TIE1,Tie1,Tyrosine-protein kinase receptor Tie-1,tie-1
|
| Uniprot Accession |
Q06806,Q06805,P35590
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSMUSG00000033191, ENSBTAG00000003777, ENSCAFG00845019831, ENSMMUG00000010660, ENSG00000066056
|
Tie1/TIE1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7075 | Pre-made Human TIE1/TIE/JTK14 siRNA oligo Duplex | 7075 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo89806 | Pre-made Rat Tie1 siRNA oligo Duplex | 89806 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21846 | Pre-made Mouse Tie1/TIE/tie-1 siRNA oligo Duplex | 21846 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702208 | Pre-made Cynomolgus/Rhesus macaque TIE1 siRNA oligo Duplex | 702208 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080986 | Pre-made Cat/Feline TIE1 siRNA oligo Duplex | 101080986 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482535 | Pre-made Dog/Canine TIE1 siRNA oligo Duplex | 482535 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280941 | Pre-made Bovines/Cattle TIE1/TIE siRNA oligo Duplex | 280941 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066563 | Pre-made Equine/Horse TIE1 siRNA oligo Duplex | 100066563 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Tie1/TIE1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98539-Ab | Human | Anti-Human Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98539-Ab | Rat | Anti-Rat Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98539-Ab | Mouse | Anti-Mouse Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98539-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98539-Ab | Cat/Feline | Anti-Cat/Feline Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98539-Ab | Dog/Canine | Anti-Dog/Canine Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98539-Ab | Bovines/Cattle | Anti-Bovines/Cattle Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98539-Ab | Equine/Horse | Anti-Equine/Horse Tie1/TIE1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Tie1/TIE1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98539-Ag | Human | Human Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98539-Ag | Rat | Rat Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98539-Ag | Mouse | Mouse Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98539-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98539-Ag | Cat/Feline | Cat/Feline Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98539-Ag | Dog/Canine | Dog/Canine Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98539-Ag | Bovines/Cattle | Bovines/Cattle Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98539-Ag | Equine/Horse | Equine/Horse Tie1/TIE1 recombinant protein | Mammalian cell | Detail |
