Explore IDUA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T98430
|
| Target Name |
IDUA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3425
|
| Gene ID |
100146682 (Equus caballus), 100505382 (Canis lupus familiaris), 101095896 (Felis catus), 106998222 (Macaca mulatta)
15932 (Mus musculus), 3425 (Homo sapiens), 360904 (Rattus norvegicus), 511050 (Bos taurus)
|
| Target Alternative Names |
IDUA,Idua,6030426D08,IDA,MPS1,MPSI
|
| Uniprot Accession |
Q01634,P48441,P35475
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Glycosaminoglycan degradation
|
| Gene Ensembl |
ENSECAG00000019632, ENSCAFG00845001029, ENSMMUG00000057764, ENSMUSG00000033540, ENSG00000127415, ENSBTAG00000007002
|
| Target Classification |
|
Pre-made viral vector of IDUA cDNA Clones/ORF Plasmid
IDUA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3425 | Pre-made Human IDUA/IDA/MPS1 siRNA oligo Duplex | 3425 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360904 | Pre-made Rat Idua siRNA oligo Duplex | 360904 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15932 | Pre-made Mouse Idua/6030426D08 siRNA oligo Duplex | 15932 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106998222 | Pre-made Cynomolgus/Rhesus macaque IDUA siRNA oligo Duplex | 106998222 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095896 | Pre-made Cat/Feline IDUA siRNA oligo Duplex | 101095896 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100505382 | Pre-made Dog/Canine IDUA siRNA oligo Duplex | 100505382 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511050 | Pre-made Bovines/Cattle IDUA siRNA oligo Duplex | 511050 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146682 | Pre-made Equine/Horse IDUA siRNA oligo Duplex | 100146682 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IDUA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98430-Ab | Human | Anti-Human IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98430-Ab | Rat | Anti-Rat IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98430-Ab | Mouse | Anti-Mouse IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98430-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98430-Ab | Cat/Feline | Anti-Cat/Feline IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98430-Ab | Dog/Canine | Anti-Dog/Canine IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98430-Ab | Bovines/Cattle | Anti-Bovines/Cattle IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98430-Ab | Equine/Horse | Anti-Equine/Horse IDUA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IDUA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98430-Ag | Human | Human IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98430-Ag | Rat | Rat IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98430-Ag | Mouse | Mouse IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98430-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98430-Ag | Cat/Feline | Cat/Feline IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98430-Ag | Dog/Canine | Dog/Canine IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98430-Ag | Bovines/Cattle | Bovines/Cattle IDUA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98430-Ag | Equine/Horse | Equine/Horse IDUA recombinant protein | Mammalian cell | Detail |
