Explore FKBP5 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
| Target ID |
GM-T98337
|
| Target Name |
FKBP5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2289
|
| Gene ID |
100053546 (Equus caballus), 101099715 (Felis catus), 14229 (Mus musculus), 2289 (Homo sapiens) 361810 (Rattus norvegicus), 481759 (Canis lupus familiaris), 535704 (Bos taurus), 718957 (Macaca mulatta)
|
| Target Alternative Names |
51 kDa FK506-binding protein (51 kDa FKBP,54 kDa progesterone receptor-associated immunophilin,AIG6,Androgen-regulated protein 6,D17Ertd592e,Dit1,FF1 antigen,FK506-binding protein 5 (FKBP-5),FKBP-5,FKBP-51),FKBP5,FKBP51,FKBP54,FKBP54 (p54),Fkbp5,HSP90-binding immunophilin,P54,PPIase,PPIase FKBP5,Peptidyl-prolyl cis-trans isomerase FKBP5,Ptg-10,Rotamase
|
| Uniprot Accession |
Q64378,Q13451
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000011304, ENSMUSG00000024222, ENSG00000096060, ENSBTAG00000047502, ENSMMUG00000011520
|
Pre-made viral vector of FKBP5 cDNA Clones/ORF Plasmid
FKBP5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2289 | Pre-made Human FKBP5/P54/AIG6 siRNA oligo Duplex | 2289 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361810 | Pre-made Rat Fkbp5 siRNA oligo Duplex | 361810 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14229 | Pre-made Mouse Fkbp5/Dit1/FKBP-5 siRNA oligo Duplex | 14229 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718957 | Pre-made Cynomolgus/Rhesus macaque FKBP5 siRNA oligo Duplex | 718957 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099715 | Pre-made Cat/Feline FKBP5 siRNA oligo Duplex | 101099715 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481759 | Pre-made Dog/Canine FKBP5 siRNA oligo Duplex | 481759 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535704 | Pre-made Bovines/Cattle FKBP5 siRNA oligo Duplex | 535704 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053546 | Pre-made Equine/Horse FKBP5 siRNA oligo Duplex | 100053546 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FKBP5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98337-Ab | Human | Anti-Human FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98337-Ab | Rat | Anti-Rat FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98337-Ab | Mouse | Anti-Mouse FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98337-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98337-Ab | Cat/Feline | Anti-Cat/Feline FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98337-Ab | Dog/Canine | Anti-Dog/Canine FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98337-Ab | Bovines/Cattle | Anti-Bovines/Cattle FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98337-Ab | Equine/Horse | Anti-Equine/Horse FKBP5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FKBP5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98337-Ag | Human | Human FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98337-Ag | Rat | Rat FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98337-Ag | Mouse | Mouse FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98337-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98337-Ag | Cat/Feline | Cat/Feline FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98337-Ag | Dog/Canine | Dog/Canine FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98337-Ag | Bovines/Cattle | Bovines/Cattle FKBP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98337-Ag | Equine/Horse | Equine/Horse FKBP5 recombinant protein | Mammalian cell | Detail |