Explore KAT6B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
| Target ID |
GM-T98275
|
| Target Name |
KAT6B
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23522
|
| Gene ID |
100064218 (Equus caballus), 101090801 (Felis catus), 23522 (Homo sapiens), 479254 (Canis lupus familiaris) 535403 (Bos taurus), 54169 (Mus musculus), 688634 (Rattus norvegicus), 704808 (Macaca mulatta)
|
| Target Alternative Names |
B130044K16Rik,GTPTS,Histone acetyltransferase KAT6B,Histone acetyltransferase MOZ2,KAT6B,Kat6b,MORF,MOZ,MOZ2,MYST-4,MYST4,Monocytic leukemia zinc finger protein-related factor,Morf,Myst4,RGD1566399,SAS2 and TIP60 protein 4 (MYST-4),YBF2/SAS3,ZC2HC6B,mKIAA0383,qkf,querkopf
|
| Uniprot Accession |
Q8WYB5,Q8BRB7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000012230, ENSG00000156650, ENSCAFG00845009903, ENSBTAG00000002920, ENSMUSG00000021767, ENSMMUG00000023488
|
Pre-made viral vector of KAT6B cDNA Clones/ORF Plasmid
KAT6B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23522 | Pre-made Human KAT6B/qkf/MORF siRNA oligo Duplex | 23522 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo688634 | Pre-made Rat Kat6b/RGD1566399 siRNA oligo Duplex | 688634 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54169 | Pre-made Mouse Kat6b/qkf/Morf siRNA oligo Duplex | 54169 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704808 | Pre-made Cynomolgus/Rhesus macaque KAT6B/MYST4 siRNA oligo Duplex | 704808 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090801 | Pre-made Cat/Feline KAT6B siRNA oligo Duplex | 101090801 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479254 | Pre-made Dog/Canine KAT6B/MYST4 siRNA oligo Duplex | 479254 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535403 | Pre-made Bovines/Cattle KAT6B/MYST4 siRNA oligo Duplex | 535403 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064218 | Pre-made Equine/Horse KAT6B/MYST4 siRNA oligo Duplex | 100064218 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KAT6B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98275-Ab | Human | Anti-Human KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98275-Ab | Rat | Anti-Rat KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98275-Ab | Mouse | Anti-Mouse KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98275-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98275-Ab | Cat/Feline | Anti-Cat/Feline KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98275-Ab | Dog/Canine | Anti-Dog/Canine KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98275-Ab | Bovines/Cattle | Anti-Bovines/Cattle KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98275-Ab | Equine/Horse | Anti-Equine/Horse KAT6B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KAT6B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98275-Ag | Human | Human KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98275-Ag | Rat | Rat KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98275-Ag | Mouse | Mouse KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98275-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98275-Ag | Cat/Feline | Cat/Feline KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98275-Ag | Dog/Canine | Dog/Canine KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98275-Ag | Bovines/Cattle | Bovines/Cattle KAT6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98275-Ag | Equine/Horse | Equine/Horse KAT6B recombinant protein | Mammalian cell | Detail |