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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T98089
|
| Target Name |
DCK
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1633
|
| Gene ID |
100054704 (Equus caballus), 101083845 (Felis catus), 13178 (Mus musculus), 1633 (Homo sapiens) 482188 (Canis lupus familiaris), 530642 (Bos taurus), 705040 (Macaca mulatta), 79127 (Rattus norvegicus)
|
| Target Alternative Names |
DCK,Dck,Deoxyadenosine kinase,Deoxycytidine kinase,Deoxyguanosine kinase,dCK
|
| Uniprot Accession |
P43346,P27707,Q3MHR2,P48769
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
Breast Cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000021782, ENSMUSG00000029366, ENSG00000156136, ENSCAFG00845011496, ENSBTAG00000012397, ENSMMUG00000030280
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of DCK cDNA Clones/ORF Plasmid
DCK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1633 | Pre-made Human DCK siRNA oligo Duplex | 1633 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79127 | Pre-made Rat Dck siRNA oligo Duplex | 79127 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13178 | Pre-made Mouse Dck siRNA oligo Duplex | 13178 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705040 | Pre-made Cynomolgus/Rhesus macaque DCK siRNA oligo Duplex | 705040 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083845 | Pre-made Cat/Feline DCK siRNA oligo Duplex | 101083845 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482188 | Pre-made Dog/Canine DCK siRNA oligo Duplex | 482188 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530642 | Pre-made Bovines/Cattle DCK siRNA oligo Duplex | 530642 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054704 | Pre-made Equine/Horse DCK siRNA oligo Duplex | 100054704 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DCK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98089-Ab | Human | Anti-Human DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T98089-Ab | Rat | Anti-Rat DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T98089-Ab | Mouse | Anti-Mouse DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T98089-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T98089-Ab | Cat/Feline | Anti-Cat/Feline DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T98089-Ab | Dog/Canine | Anti-Dog/Canine DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T98089-Ab | Bovines/Cattle | Anti-Bovines/Cattle DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T98089-Ab | Equine/Horse | Anti-Equine/Horse DCK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DCK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98089-Ag | Human | Human DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98089-Ag | Rat | Rat DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98089-Ag | Mouse | Mouse DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98089-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98089-Ag | Cat/Feline | Cat/Feline DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98089-Ag | Dog/Canine | Dog/Canine DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98089-Ag | Bovines/Cattle | Bovines/Cattle DCK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98089-Ag | Equine/Horse | Equine/Horse DCK recombinant protein | Mammalian cell | Detail |