Explore GUCY2C gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]
| Target ID |
GM-T97947
|
| Target Name |
GUCY2C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2984
|
| Gene ID |
100063810 (Equus caballus), 101095109 (Felis catus), 14917 (Mus musculus), 25711 (Rattus norvegicus)
282244 (Bos taurus), 2984 (Homo sapiens), 486671 (Canis lupus familiaris), 699191 (Macaca mulatta)
|
| Target Alternative Names |
DIAR6,GC-C,GCC,GUC2C,GUCY2C,Gcc,Guanylyl cyclase C,Gucy2c,HSER,Heat-stable enterotoxin receptor (STA receptor,Intestinal guanylate cyclase,MECIL,MUCIL,STAR,hSTAR)
|
| Uniprot Accession |
Q3UWA6,P23897,P25092
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSMUSG00000042638, ENSBTAG00000019722, ENSG00000070019, ENSCAFG00845022380, ENSMMUG00000057471
|
| Target Classification |
Checkpoint-Immuno Oncology
|
GUCY2C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2984 | Pre-made Human GUCY2C/GCC/GC-C siRNA oligo Duplex | 2984 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25711 | Pre-made Rat Gucy2c/GCC siRNA oligo Duplex | 25711 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14917 | Pre-made Mouse Gucy2c/Gcc/GC-C siRNA oligo Duplex | 14917 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699191 | Pre-made Cynomolgus/Rhesus macaque GUCY2C siRNA oligo Duplex | 699191 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095109 | Pre-made Cat/Feline GUCY2C siRNA oligo Duplex | 101095109 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486671 | Pre-made Dog/Canine GUCY2C siRNA oligo Duplex | 486671 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282244 | Pre-made Bovines/Cattle GUCY2C siRNA oligo Duplex | 282244 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063810 | Pre-made Equine/Horse GUCY2C siRNA oligo Duplex | 100063810 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GUCY2C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97947-Ab | Human | Anti-Human GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T97947-Ab | Rat | Anti-Rat GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T97947-Ab | Mouse | Anti-Mouse GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T97947-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T97947-Ab | Cat/Feline | Anti-Cat/Feline GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T97947-Ab | Dog/Canine | Anti-Dog/Canine GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T97947-Ab | Bovines/Cattle | Anti-Bovines/Cattle GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T97947-Ab | Equine/Horse | Anti-Equine/Horse GUCY2C monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GUCY2C VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97947-Ag | Human | Human GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T97947-Ag | Rat | Rat GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T97947-Ag | Mouse | Mouse GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T97947-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T97947-Ag | Cat/Feline | Cat/Feline GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T97947-Ag | Dog/Canine | Dog/Canine GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T97947-Ag | Bovines/Cattle | Bovines/Cattle GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T97947-Ag | Equine/Horse | Equine/Horse GUCY2C VLP (virus-like particle) | HEK293 | Products Developing |
