Explore ZAK/MAP3K20/MLTK gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T97821
|
| Target Name |
ZAK/MAP3K20/MLTK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51776
|
| Gene ID |
100053153 (Equus caballus), 101094038 (Felis catus), 311743 (Rattus norvegicus), 478802 (Canis lupus familiaris)
51776 (Homo sapiens), 519251 (Bos taurus), 65964 (Mus musculus), 698274 (Macaca mulatta)
|
| Target Alternative Names |
MAP3K20,Map3k20,Zak,MLTK,RGD1561394,ZAK,pk,AZK,MLT,MRK,CNM6,MLK7,SFMMP,mlklak,MLTKbeta,MLTKalpha,HCCS-4,B230120H23Rik
|
| Uniprot Accession |
Q9NYL2,Q9ESL4
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway
|
| Gene Ensembl |
ENSECAG00000000477, ENSCAFG00845029200, ENSG00000091436, ENSBTAG00000001083, ENSMUSG00000004085, ENSMMUG00000014672
|
| Target Classification |
Kinase
|
Pre-made viral vector of ZAK/MAP3K20/MLTK cDNA Clones/ORF Plasmid
ZAK/MAP3K20/MLTK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51776 | Pre-made Human MAP3K20/pk/AZK siRNA oligo Duplex | 51776 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo311743 | Pre-made Rat Map3k20/Zak/MLTK siRNA oligo Duplex | 311743 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65964 | Pre-made Mouse Map3k20/MRK/Zak siRNA oligo Duplex | 65964 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698274 | Pre-made Cynomolgus/Rhesus macaque MAP3K20/ZAK siRNA oligo Duplex | 698274 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094038 | Pre-made Cat/Feline MAP3K20 siRNA oligo Duplex | 101094038 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478802 | Pre-made Dog/Canine MAP3K20/ZAK siRNA oligo Duplex | 478802 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519251 | Pre-made Bovines/Cattle MAP3K20/MRK/ZAK siRNA oligo Duplex | 519251 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053153 | Pre-made Equine/Horse MAP3K20 siRNA oligo Duplex | 100053153 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ZAK/MAP3K20/MLTK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97821-Ab | Human | Anti-Human ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T97821-Ab | Rat | Anti-Rat ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T97821-Ab | Mouse | Anti-Mouse ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T97821-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T97821-Ab | Cat/Feline | Anti-Cat/Feline ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T97821-Ab | Dog/Canine | Anti-Dog/Canine ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T97821-Ab | Bovines/Cattle | Anti-Bovines/Cattle ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T97821-Ab | Equine/Horse | Anti-Equine/Horse ZAK/MAP3K20/MLTK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ZAK/MAP3K20/MLTK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97821-Ag | Human | Human ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T97821-Ag | Rat | Rat ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T97821-Ag | Mouse | Mouse ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T97821-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T97821-Ag | Cat/Feline | Cat/Feline ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T97821-Ag | Dog/Canine | Dog/Canine ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T97821-Ag | Bovines/Cattle | Bovines/Cattle ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T97821-Ag | Equine/Horse | Equine/Horse ZAK/MAP3K20/MLTK recombinant protein | Mammalian cell | Detail |
