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Target
sublocation: Secreted Protein/Potential Cytokines.
This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
| Target ID |
GM-T97765
|
| Target Name |
MIP-1 Alpha/CCL3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6348
|
| Gene ID |
6348 (Homo sapiens)
|
| Target Alternative Names |
C-C motif chemokine 3,CCL3,G0/G1 switch regulatory protein 19-1,G0S19-1,LD78,LD78ALPHA,MIP-1 Alpha,MIP-1-alpha,MIP1A,Macrophage inflammatory protein 1-alpha (MIP-1-alpha),PAT 464.1,SCI,SCYA3,SIS-beta,Small-inducible cytokine A3,Tonsillar lymphocyte LD78 alpha protein
|
| Uniprot Accession |
P10147
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Toll-like receptor signaling pathway, Chagas disease, Human cytomegalovirus infection, Rheumatoid arthritis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSG00000277632
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of MIP-1 Alpha/CCL3 cDNA Clones/ORF Plasmid
MIP-1 Alpha/CCL3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6348 | Pre-made Human CCL3/SCI/LD78 siRNA oligo Duplex | 6348 | Human | In-vitro grade; in-vivo grade | Detail |
MIP-1 Alpha/CCL3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97765-Ab | Human | Anti-Human MIP-1 Alpha/CCL3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
MIP-1 Alpha/CCL3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97765-Ag | Human | Human MIP-1 Alpha/CCL3 recombinant protein | Mammalian cell | Detail |
