Explore PPT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]
| Target ID |
GM-T97740
|
| Target Name |
PPT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5538
|
| Gene ID |
100068301 (Equus caballus), 101097408 (Felis catus), 19063 (Mus musculus), 281421 (Bos taurus)
29411 (Rattus norvegicus), 475316 (Canis lupus familiaris), 5538 (Homo sapiens), 693377 (Macaca mulatta)
|
| Target Alternative Names |
9530043G02Rik,CLN1,D4Ertd184e,INCL,PPT,PPT-1,PPT1,Palmitoyl-protein hydrolase 1,Palmitoyl-protein thioesterase 1,Ppt,Ppt1
|
| Uniprot Accession |
O88531,P45478,P45479,P50897
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Lysosome
|
| Gene Ensembl |
ENSECAG00000017370, ENSMUSG00000028657, ENSBTAG00000013367, ENSCAFG00845010701, ENSG00000131238, ENSMMUG00000009189
|
Pre-made viral vector of PPT1 cDNA Clones/ORF Plasmid
PPT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5538 | Pre-made Human PPT1/PPT/CLN1 siRNA oligo Duplex | 5538 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29411 | Pre-made Rat Ppt1/Ppt siRNA oligo Duplex | 29411 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19063 | Pre-made Mouse Ppt1/PPT/CLN1 siRNA oligo Duplex | 19063 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693377 | Pre-made Cynomolgus/Rhesus macaque PPT1 siRNA oligo Duplex | 693377 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097408 | Pre-made Cat/Feline PPT1 siRNA oligo Duplex | 101097408 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475316 | Pre-made Dog/Canine PPT1 siRNA oligo Duplex | 475316 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281421 | Pre-made Bovines/Cattle PPT1/CLN1 siRNA oligo Duplex | 281421 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068301 | Pre-made Equine/Horse PPT1 siRNA oligo Duplex | 100068301 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PPT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97740-Ab | Human | Anti-Human PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T97740-Ab | Rat | Anti-Rat PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T97740-Ab | Mouse | Anti-Mouse PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T97740-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T97740-Ab | Cat/Feline | Anti-Cat/Feline PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T97740-Ab | Dog/Canine | Anti-Dog/Canine PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T97740-Ab | Bovines/Cattle | Anti-Bovines/Cattle PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T97740-Ab | Equine/Horse | Anti-Equine/Horse PPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PPT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97740-Ag | Human | Human PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T97740-Ag | Rat | Rat PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T97740-Ag | Mouse | Mouse PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T97740-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T97740-Ag | Cat/Feline | Cat/Feline PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T97740-Ag | Dog/Canine | Dog/Canine PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T97740-Ag | Bovines/Cattle | Bovines/Cattle PPT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T97740-Ag | Equine/Horse | Equine/Horse PPT1 recombinant protein | Mammalian cell | Detail |
