Explore MTNR1A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T97613
|
| Target Name |
MTNR1A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4543
|
| Gene ID |
100056423 (Equus caballus), 101098297 (Felis catus), 114211 (Rattus norvegicus), 17773 (Mus musculus)
4543 (Homo sapiens), 482904 (Canis lupus familiaris), 539948 (Bos taurus), 702686 (Macaca mulatta)
|
| Target Alternative Names |
MEL-1A-R,MR,MT1,MTNR1A,Mel-1A-R,Mel1a receptor,MelR,Melatonin receptor type 1A,Mtnr1a
|
| Uniprot Accession |
P49218,Q61184,P48039,O02769
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Circadian entrainment
|
| Gene Ensembl |
ENSECAG00000000202, ENSMUSG00000054764, ENSG00000168412, ENSBTAG00000046938, ENSMMUG00000018050
|
| Target Classification |
GPCR
|
Pre-made viral vector of MTNR1A cDNA Clones/ORF Plasmid
MTNR1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4543 | Pre-made Human MTNR1A/MT1/MEL-1A-R siRNA oligo Duplex | 4543 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114211 | Pre-made Rat Mtnr1a siRNA oligo Duplex | 114211 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17773 | Pre-made Mouse Mtnr1a/MR/MelR siRNA oligo Duplex | 17773 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702686 | Pre-made Cynomolgus/Rhesus macaque MTNR1A siRNA oligo Duplex | 702686 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098297 | Pre-made Cat/Feline MTNR1A siRNA oligo Duplex | 101098297 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482904 | Pre-made Dog/Canine MTNR1A siRNA oligo Duplex | 482904 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539948 | Pre-made Bovines/Cattle MTNR1A/MT1/Mel-1A-R siRNA oligo Duplex | 539948 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056423 | Pre-made Equine/Horse MTNR1A siRNA oligo Duplex | 100056423 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MTNR1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97613-Ab | Human | Anti-Human MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T97613-Ab | Rat | Anti-Rat MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T97613-Ab | Mouse | Anti-Mouse MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T97613-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T97613-Ab | Cat/Feline | Anti-Cat/Feline MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T97613-Ab | Dog/Canine | Anti-Dog/Canine MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T97613-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T97613-Ab | Equine/Horse | Anti-Equine/Horse MTNR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MTNR1A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97613-Ag | Human | Human MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T97613-Ag | Rat | Rat MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T97613-Ag | Mouse | Mouse MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T97613-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T97613-Ag | Cat/Feline | Cat/Feline MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T97613-Ag | Dog/Canine | Dog/Canine MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T97613-Ag | Bovines/Cattle | Bovines/Cattle MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T97613-Ag | Equine/Horse | Equine/Horse MTNR1A VLP (virus-like particle) | HEK293 | Products Developing |
