Explore LNPEP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T97537
|
| Target Name |
LNPEP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4012
|
| Gene ID |
100073222 (Equus caballus), 101083321 (Felis catus), 171105 (Rattus norvegicus), 240028 (Mus musculus)
4012 (Homo sapiens), 488896 (Canis lupus familiaris), 521633 (Bos taurus), 703949 (Macaca mulatta)
|
| Target Alternative Names |
2010309L07Rik,4732490P18Rik,CAP,Cystinyl aminopeptidase,GP160,IRAP,Insulin-regulated membrane aminopeptidase,Insulin-responsive aminopeptidase (IRAP),LNPEP,Leucyl-cystinyl aminopeptidase,Lnpep,OTase,Oxytocinase (OTase),P-LAP,PLAP,Placental leucine aminopeptidase (P-LAP),Vp165,gp160,vp165
|
| Uniprot Accession |
P97629,Q8C129,Q9UIQ6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
IgA glomerulonephritis
|
| Disease from KEGG |
Renin-angiotensin system
|
| Gene Ensembl |
ENSECAG00000021790, ENSMUSG00000023845, ENSG00000113441, ENSCAFG00845002437, ENSBTAG00000019900, ENSMMUG00000018542
|
LNPEP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4012 | Pre-made Human LNPEP/CAP/IRAP siRNA oligo Duplex | 4012 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171105 | Pre-made Rat Lnpep/IRAP/GP160 siRNA oligo Duplex | 171105 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo240028 | Pre-made Mouse Lnpep/CAP/IRAP siRNA oligo Duplex | 240028 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703949 | Pre-made Cynomolgus/Rhesus macaque LNPEP siRNA oligo Duplex | 703949 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083321 | Pre-made Cat/Feline LNPEP siRNA oligo Duplex | 101083321 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488896 | Pre-made Dog/Canine LNPEP siRNA oligo Duplex | 488896 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521633 | Pre-made Bovines/Cattle LNPEP siRNA oligo Duplex | 521633 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073222 | Pre-made Equine/Horse LNPEP siRNA oligo Duplex | 100073222 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LNPEP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T97537-Ab | Human | Anti-Human LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T97537-Ab | Rat | Anti-Rat LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T97537-Ab | Mouse | Anti-Mouse LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T97537-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T97537-Ab | Cat/Feline | Anti-Cat/Feline LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T97537-Ab | Dog/Canine | Anti-Dog/Canine LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T97537-Ab | Bovines/Cattle | Anti-Bovines/Cattle LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T97537-Ab | Equine/Horse | Anti-Equine/Horse LNPEP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LNPEP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T97537-Ag | Human | Human LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T97537-Ag | Rat | Rat LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T97537-Ag | Mouse | Mouse LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T97537-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T97537-Ag | Cat/Feline | Cat/Feline LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T97537-Ag | Dog/Canine | Dog/Canine LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T97537-Ag | Bovines/Cattle | Bovines/Cattle LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T97537-Ag | Equine/Horse | Equine/Horse LNPEP VLP (virus-like particle) | HEK293 | Products Developing |
