CD43/SPN Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

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Target sublocation: Transmembrane Protein.
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Pre-made viral vector of CD43/SPN cDNA Clones/ORF Plasmid

CD43/SPN siRNA/miRNA/oligo for RNA interfence (RNAi)

CD43/SPN antibody/GMab

CD43/SPN VLP (virus-like particle)/protein