Explore DKK3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T96916
|
| Target Name |
DKK3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27122
|
| Gene ID |
100055937 (Equus caballus), 101093392 (Felis catus), 171548 (Rattus norvegicus), 27122 (Homo sapiens)
476857 (Canis lupus familiaris), 506627 (Bos taurus), 50781 (Mus musculus), 701549 (Macaca mulatta)
|
| Target Alternative Names |
DKK3,Dkk3,REIC/Dkk-3,p29,Reic,RIG,CRRL,REIC,dkk-3,mDkk-3
|
| Uniprot Accession |
Q9UBP4,Q9QUN9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Ovary Cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000022804, ENSG00000050165, ENSCAFG00845017299, ENSMUSG00000030772, ENSMMUG00000022862
|
| Target Classification |
|
Pre-made viral vector of DKK3 cDNA Clones/ORF Plasmid
DKK3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27122 | Pre-made Human DKK3/RIG/CRRL siRNA oligo Duplex | 27122 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171548 | Pre-made Rat Dkk3/p29/Reic siRNA oligo Duplex | 171548 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50781 | Pre-made Mouse Dkk3/dkk-3/mDkk-3 siRNA oligo Duplex | 50781 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701549 | Pre-made Cynomolgus/Rhesus macaque DKK3 siRNA oligo Duplex | 701549 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093392 | Pre-made Cat/Feline DKK3/REIC/Dkk-3 siRNA oligo Duplex | 101093392 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476857 | Pre-made Dog/Canine DKK3/REIC/Dkk-3 siRNA oligo Duplex | 476857 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506627 | Pre-made Bovines/Cattle DKK3 siRNA oligo Duplex | 506627 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055937 | Pre-made Equine/Horse DKK3 siRNA oligo Duplex | 100055937 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DKK3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T96916-Ab | Human | Anti-Human DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T96916-Ab | Rat | Anti-Rat DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T96916-Ab | Mouse | Anti-Mouse DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T96916-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T96916-Ab | Cat/Feline | Anti-Cat/Feline DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T96916-Ab | Dog/Canine | Anti-Dog/Canine DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T96916-Ab | Bovines/Cattle | Anti-Bovines/Cattle DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T96916-Ab | Equine/Horse | Anti-Equine/Horse DKK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DKK3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T96916-Ag | Human | Human DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T96916-Ag | Rat | Rat DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T96916-Ag | Mouse | Mouse DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T96916-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T96916-Ag | Cat/Feline | Cat/Feline DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T96916-Ag | Dog/Canine | Dog/Canine DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T96916-Ag | Bovines/Cattle | Bovines/Cattle DKK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T96916-Ag | Equine/Horse | Equine/Horse DKK3 recombinant protein | Mammalian cell | Detail |
