Explore GUSB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014]
| Target ID |
GM-T96413
|
| Target Name |
GUSB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2990
|
| Gene ID |
100037416 (Equus caballus), 110006 (Mus musculus), 24434 (Rattus norvegicus), 2990 (Homo sapiens)
403831 (Canis lupus familiaris), 493879 (Felis catus), 515687 (Bos taurus)
|
| Target Alternative Names |
Ac2-223,BG,Beta-G1,Beta-glucuronidase,GUSB,Gur,Gus,Gus-r,Gus-s,Gus-t,Gus-u,Gusb,Gut,MPS7,asd,g
|
| Uniprot Accession |
P12265,P06760,P08236,O18835,O97524
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Pentose and glucuronate interconversions, Lysosome, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Porphyrin metabolism
|
| Gene Ensembl |
ENSECAG00000014688, ENSMUSG00000025534, ENSG00000169919, ENSCAFG00845013255, ENSBTAG00000000704
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of GUSB cDNA Clones/ORF Plasmid
GUSB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2990 | Pre-made Human GUSB/BG/MPS7 siRNA oligo Duplex | 2990 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24434 | Pre-made Rat Gusb/Gus-s/Ac2-223 siRNA oligo Duplex | 24434 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110006 | Pre-made Mouse Gusb/g/Gur siRNA oligo Duplex | 110006 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493879 | Pre-made Cat/Feline GUSB siRNA oligo Duplex | 493879 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403831 | Pre-made Dog/Canine GUSB siRNA oligo Duplex | 403831 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515687 | Pre-made Bovines/Cattle GUSB siRNA oligo Duplex | 515687 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100037416 | Pre-made Equine/Horse GUSB siRNA oligo Duplex | 100037416 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GUSB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T96413-Ab | Human | Anti-Human GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T96413-Ab | Rat | Anti-Rat GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T96413-Ab | Mouse | Anti-Mouse GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T96413-Ab | Cat/Feline | Anti-Cat/Feline GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T96413-Ab | Dog/Canine | Anti-Dog/Canine GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T96413-Ab | Bovines/Cattle | Anti-Bovines/Cattle GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T96413-Ab | Equine/Horse | Anti-Equine/Horse GUSB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GUSB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T96413-Ag | Human | Human GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T96413-Ag | Rat | Rat GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T96413-Ag | Mouse | Mouse GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T96413-Ag | Cat/Feline | Cat/Feline GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T96413-Ag | Dog/Canine | Dog/Canine GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T96413-Ag | Bovines/Cattle | Bovines/Cattle GUSB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T96413-Ag | Equine/Horse | Equine/Horse GUSB recombinant protein | Mammalian cell | Detail |
