Explore Ezrin/EZR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T96256
|
| Target Name |
Ezrin/EZR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7430
|
| Gene ID |
100059467 (Equus caballus), 101092519 (Felis catus), 22350 (Mus musculus), 281574 (Bos taurus)
484056 (Canis lupus familiaris), 54319 (Rattus norvegicus), 704716 (Macaca mulatta), 7430 (Homo sapiens)
|
| Target Alternative Names |
CVIL,CVL,Cytovillin,EZR,Ezr,Ezrin,HEL-S-105,VIL2,Vil2,Villin-2,p81
|
| Uniprot Accession |
P26040,P31976,P31977,P15311
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Tight junction, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Gastric acid secretion, Pathogenic Escherichia coli infection, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000018333, ENSMUSG00000052397, ENSBTAG00000010347, ENSCAFG00845001373, ENSMMUG00000019457, ENSG00000092820
|
Pre-made viral vector of Ezrin/EZR cDNA Clones/ORF Plasmid
Ezrin/EZR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7430 | Pre-made Human EZR/CVL/CVIL siRNA oligo Duplex | 7430 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54319 | Pre-made Rat Ezr/Vil2 siRNA oligo Duplex | 54319 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22350 | Pre-made Mouse Ezr/p81/Vil2 siRNA oligo Duplex | 22350 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704716 | Pre-made Cynomolgus/Rhesus macaque EZR siRNA oligo Duplex | 704716 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092519 | Pre-made Cat/Feline EZR siRNA oligo Duplex | 101092519 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484056 | Pre-made Dog/Canine EZR/VIL2 siRNA oligo Duplex | 484056 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281574 | Pre-made Bovines/Cattle EZR/VIL2 siRNA oligo Duplex | 281574 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059467 | Pre-made Equine/Horse EZR siRNA oligo Duplex | 100059467 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Ezrin/EZR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T96256-Ab | Human | Anti-Human Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T96256-Ab | Rat | Anti-Rat Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T96256-Ab | Mouse | Anti-Mouse Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T96256-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T96256-Ab | Cat/Feline | Anti-Cat/Feline Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T96256-Ab | Dog/Canine | Anti-Dog/Canine Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T96256-Ab | Bovines/Cattle | Anti-Bovines/Cattle Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T96256-Ab | Equine/Horse | Anti-Equine/Horse Ezrin/EZR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Ezrin/EZR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T96256-Ag | Human | Human Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T96256-Ag | Rat | Rat Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T96256-Ag | Mouse | Mouse Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T96256-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T96256-Ag | Cat/Feline | Cat/Feline Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T96256-Ag | Dog/Canine | Dog/Canine Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T96256-Ag | Bovines/Cattle | Bovines/Cattle Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T96256-Ag | Equine/Horse | Equine/Horse Ezrin/EZR VLP (virus-like particle) | HEK293 | Products Developing |
