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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]
| Target ID |
GM-T95913
|
| Target Name |
PIK3CG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5294
|
| Gene ID |
100050532 (Equus caballus), 101096215 (Felis catus), 298947 (Rattus norvegicus), 30955 (Mus musculus)
483266 (Canis lupus familiaris), 5294 (Homo sapiens), 530001 (Bos taurus), 698857 (Macaca mulatta)
|
| Target Alternative Names |
5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma (PtdIns-3-kinase subunit p110-gamma,5-bisphosphate 3-kinase catalytic subunit gamma isoform,5830428L06Rik,IMD97,PI3-kinase subunit gamma,PI3CG,PI3K,PI3K-gamma,PI3Kgamma,PIK3,PIK3CG,Phosphatidylinositol 4,Phosphoinositide-3-kinase catalytic gamma polypeptide,Pi3k,Pik3cg,PtdIns-3-kinase subunit gamma,Serine/threonine protein kinase PIK3CG,p110gamma,p110gamma),p120-PI3K
|
| Uniprot Accession |
Q9JHG7,P48736
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, cGMP-PKG signaling pathway, Chemokine signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, Platelet activation, Cholinergic synapse, Oxytocin signaling pathway, Toxoplasmosis, Kaposi sarcoma-associated herpesvirus infection
|
| Gene Ensembl |
ENSECAG00000019708, ENSMUSG00000020573, ENSCAFG00845026701, ENSG00000105851, ENSBTAG00000020848, ENSMMUG00000011385
|
| Target Classification |
Kinase
|
Pre-made viral vector of PIK3CG cDNA Clones/ORF Plasmid
PIK3CG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5294 | Pre-made Human PIK3CG/PI3K/PIK3 siRNA oligo Duplex | 5294 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298947 | Pre-made Rat Pik3cg/Pi3k siRNA oligo Duplex | 298947 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo30955 | Pre-made Mouse Pik3cg/PI3Kgamma/p110gamma siRNA oligo Duplex | 30955 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698857 | Pre-made Cynomolgus/Rhesus macaque PIK3CG siRNA oligo Duplex | 698857 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096215 | Pre-made Cat/Feline PIK3CG siRNA oligo Duplex | 101096215 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483266 | Pre-made Dog/Canine PIK3CG siRNA oligo Duplex | 483266 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530001 | Pre-made Bovines/Cattle PIK3CG siRNA oligo Duplex | 530001 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050532 | Pre-made Equine/Horse PIK3CG siRNA oligo Duplex | 100050532 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PIK3CG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T95913-Ab | Human | Anti-Human PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T95913-Ab | Rat | Anti-Rat PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T95913-Ab | Mouse | Anti-Mouse PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T95913-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T95913-Ab | Cat/Feline | Anti-Cat/Feline PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T95913-Ab | Dog/Canine | Anti-Dog/Canine PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T95913-Ab | Bovines/Cattle | Anti-Bovines/Cattle PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T95913-Ab | Equine/Horse | Anti-Equine/Horse PIK3CG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PIK3CG VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T95913-Ag | Human | Human PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T95913-Ag | Rat | Rat PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T95913-Ag | Mouse | Mouse PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T95913-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T95913-Ag | Cat/Feline | Cat/Feline PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T95913-Ag | Dog/Canine | Dog/Canine PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T95913-Ag | Bovines/Cattle | Bovines/Cattle PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T95913-Ag | Equine/Horse | Equine/Horse PIK3CG VLP (virus-like particle) | HEK293 | Products Developing |
