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Target
sublocation: Introcelluar Protein.
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T95736
|
| Target Name |
MAP3K14
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9020
|
| Gene ID |
100050140 (Equus caballus), 101083468 (Felis catus), 360640 (Rattus norvegicus), 490926 (Canis lupus familiaris)
508367 (Bos taurus), 53859 (Mus musculus), 716258 (Macaca mulatta), 9020 (Homo sapiens)
|
| Target Alternative Names |
FTDCR1B,HS,HSNIK,IMD112,MAP3K14,Map3k14,Mitogen-activated protein kinase kinase kinase 14,NF-kappa-beta-inducing kinase (HsNIK),NIK,Nik,Serine/threonine-protein kinase NIK,aly
|
| Uniprot Accession |
Q9WUL6,Q99558
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway, NF-kappa B signaling pathway, Apoptosis, Osteoclast differentiation, C-type lectin receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Intestinal immune network for IgA production, Alcoholic liver disease, Epithelial cell signaling in Helicobacter pylori infection, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000014800, ENSCAFG00845005731, ENSBTAG00000007084, ENSMUSG00000020941, ENSMMUG00000007863, ENSG00000006062
|
| Target Classification |
Kinase
|
Pre-made viral vector of MAP3K14 cDNA Clones/ORF Plasmid
MAP3K14 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9020 | Pre-made Human MAP3K14/HS/NIK siRNA oligo Duplex | 9020 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360640 | Pre-made Rat Map3k14 siRNA oligo Duplex | 360640 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo53859 | Pre-made Mouse Map3k14/Nik/aly siRNA oligo Duplex | 53859 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716258 | Pre-made Cynomolgus/Rhesus macaque MAP3K14 siRNA oligo Duplex | 716258 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083468 | Pre-made Cat/Feline MAP3K14 siRNA oligo Duplex | 101083468 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490926 | Pre-made Dog/Canine MAP3K14 siRNA oligo Duplex | 490926 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508367 | Pre-made Bovines/Cattle MAP3K14 siRNA oligo Duplex | 508367 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050140 | Pre-made Equine/Horse MAP3K14 siRNA oligo Duplex | 100050140 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAP3K14 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T95736-Ab | Human | Anti-Human MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T95736-Ab | Rat | Anti-Rat MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T95736-Ab | Mouse | Anti-Mouse MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T95736-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T95736-Ab | Cat/Feline | Anti-Cat/Feline MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T95736-Ab | Dog/Canine | Anti-Dog/Canine MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T95736-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T95736-Ab | Equine/Horse | Anti-Equine/Horse MAP3K14 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAP3K14 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T95736-Ag | Human | Human MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T95736-Ag | Rat | Rat MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T95736-Ag | Mouse | Mouse MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T95736-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T95736-Ag | Cat/Feline | Cat/Feline MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T95736-Ag | Dog/Canine | Dog/Canine MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T95736-Ag | Bovines/Cattle | Bovines/Cattle MAP3K14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T95736-Ag | Equine/Horse | Equine/Horse MAP3K14 recombinant protein | Mammalian cell | Detail |
